Polr2f RNA polymerase II, I and III subunit F [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Polr2fprovided by RGD
Official Full Name: RNA polymerase II, I and III subunit Fprovided by RGD
Primary source: RGD:708567
See related: EnsemblRapid:ENSRNOG00000011214 AllianceGenome:RGD:708567
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2F (RNA polymerase II, I and III subunit F). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Heart (RPKM 110.9), Kidney (RPKM 72.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (112592977..112604681)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (110712528..110724234)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (120380543..120392214)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

BE105428 (e-PCR)
- UniSTS:245837

RH132698 (e-PCR)
- UniSTS:215981

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-directed 5'-3' RNA polymerase activity	TAS Traceable Author Statement more info	PubMed
contributes_to RNA polymerase I activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to RNA polymerase II activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to RNA polymerase III activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in tRNA transcription by RNA polymerase III	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase I	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase I	TAS Traceable Author Statement more info	PubMed
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
involved_in transcription by RNA polymerase II	TAS Traceable Author Statement more info	PubMed
involved_in transcription by RNA polymerase III	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
part_of RNA polymerase I complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase I complex	ISO Inferred from Sequence Orthology more info
part_of RNA polymerase I complex	TAS Traceable Author Statement more info	PubMed
part_of RNA polymerase II, core complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase II, core complex	ISO Inferred from Sequence Orthology more info
part_of RNA polymerase II, core complex	ISS Inferred from Sequence or Structural Similarity more info
part_of RNA polymerase II, core complex	TAS Traceable Author Statement more info	PubMed
part_of RNA polymerase III complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase III complex	ISO Inferred from Sequence Orthology more info
part_of RNA polymerase III complex	TAS Traceable Author Statement more info	PubMed
located_in fibrillar center	IEA Inferred from Electronic Annotation more info
located_in fibrillar center	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: DNA-directed RNA polymerases I, II, and III subunit RPABC2

Names: DNA-directed RNA polymerase II subunit F; RNA polymerase II subunit F; RNA polymerases I, II, and III subunit ABC2; RPB6 homolog; polymerase (RNA) II (DNA directed) polypeptide F; polymerase (RNA) II subunit F; polymerase II

NP_112625.1

EC 2.7.7.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_031335.3 → NP_112625.1 DNA-directed RNA polymerases I, II, and III subunit RPABC2

See identical proteins and their annotated locations for NP_112625.1

Status: PROVISIONAL

Source sequence(s)

AB017711

UniProtKB/Swiss-Prot

O88828

UniProtKB/TrEMBL

A6HSQ1

Related

ENSRNOP00000015009.3, ENSRNOT00000015009.8

Conserved Domains (1) summary

PLN00152
Location:26 → 127

PLN00152; DNA-directed RNA polymerase; Provisional