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    PF3D7_1443900 heat shock protein 90, putative [ Plasmodium falciparum 3D7 ]

    Gene ID: 811999, updated on 17-May-2024

    Summary

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    Gene symbol
    PF3D7_1443900
    Gene description
    heat shock protein 90, putative
    Primary source
    PlasmoDB:PF3D7_1443900
    Locus tag
    PF3D7_1443900
    See related
    VEuPathDB:PF3D7_1443900
    Gene type
    protein coding
    RNA name
    heat shock protein 90, putative
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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    Genomic context

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    See PF3D7_1443900 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    1
    Sequence:
    Chromosome: 14; NC_037283.1 (1797288..1800071)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene dephospho-CoA kinase, putative Neighboring gene pre-mRNA-splicing factor CWC24, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved Plasmodium protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients. Pallavi R, et al. Malar J, 2010 Aug 19. PMID 20719001, Free PMC Article
    2. Structure of the ATP-binding domain of Plasmodium falciparum Hsp90. Corbett KD, et al. Proteins, 2010 Oct. PMID 20635416, Free PMC Article
    3. Characterization of Plasmodium falciparum co-chaperone p23: its intrinsic chaperone activity and interaction with Hsp90. Chua CS, et al. Cell Mol Life Sci, 2010 May. PMID 20140477, Free PMC Article
    4. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article
    5. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Studies indicat that the results should aid in the structural understanding of Hsp90-drug interactions and provide a scaffold for future drug-discovery efforts.
      Title: Structure of the ATP-binding domain of Plasmodium falciparum Hsp90.
    2. this study demonstrates an intimate involvement of parasite-encoded chaperones, PfHsp90 in particular, in defining pathogenesis of malaria.
      Title: Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients.
    3. This study has provided experimental evidence for the inherent chaperone function of Pfp23 and its interaction with PfHsp90, a sequel widely required for client protein activation.
      Title: Characterization of Plasmodium falciparum co-chaperone p23: its intrinsic chaperone activity and interaction with Hsp90.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GeneDB

    Component Evidence Code Pubs
    located_in apicoplast HDA PubMed 

    General protein information

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    Preferred Names
    heat shock protein 90, putative

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      1797288..1800071
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348555.1 → XP_001348591.1  heat shock protein 90, putative [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348591.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V0D7, A0A024VK29, A0A024WHZ6, A0A024WYZ8, A0A0L1I8W6, A0A0L7LY43, Q8IL32, W4I7Z9, W4IVP5, W7EU68, W7FHF1, W7JLF0
      Conserved Domains (1) summary
      PRK05218
      Location:97 → 801
      PRK05218; heat shock protein 90; Provisional
    Nucleotide Protein
    Heading Accession and Version

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