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    OR4F17 olfactory receptor family 4 subfamily F member 17 [ Homo sapiens (human) ]

    Gene ID: 81099, updated on 2-Nov-2024

    Summary

    Official Symbol
    OR4F17provided by HGNC
    Official Full Name
    olfactory receptor family 4 subfamily F member 17provided by HGNC
    Primary source
    HGNC:HGNC:15381
    See related
    Ensembl:ENSG00000176695 AllianceGenome:HGNC:15381
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR4F5; OR4F18; OR4F19; OR4F11P
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See OR4F17 in Genome Data Viewer
    Location:
    19p13.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (107104..113156)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (58109..64470)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (107104..113156)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily G member 3 pseudogene Neighboring gene olfactory receptor family 4 subfamily G member 1 pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:146969-147469 Neighboring gene WBP1L pseudogene 11 Neighboring gene olfactory receptor family 4 subfamily F member 8 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 4F17
    Names
    olfactory receptor 4F11
    olfactory receptor 4F18
    olfactory receptor 4F19
    olfactory receptor, family 4, subfamily F, member 11 pseudogene
    olfactory receptor, family 4, subfamily F, member 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005240.3NP_001005240.1  olfactory receptor 4F17 isoform 1

      See identical proteins and their annotated locations for NP_001005240.1

      Status: VALIDATED

      Source sequence(s)
      AC008977
      Consensus CDS
      CCDS32854.1
      UniProtKB/Swiss-Prot
      B2RNE8, Q8NGA8
      UniProtKB/TrEMBL
      A0A126GVH1, A0A126GWG7, A0A126GWN0
      Related
      ENSP00000467301.1, ENST00000585993.3
      Conserved Domains (2) summary
      pfam00001
      Location:34280
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:24294
      7tm_4; Olfactory receptor
    2. NM_001429985.1NP_001416914.1  olfactory receptor 4F17 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC008977
      UniProtKB/TrEMBL
      A0A2U3U062
      Related
      ENSP00000493422.2, ENST00000618231.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      107104..113156
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      58109..64470
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)