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    Nup210l nucleoporin 210-like [ Mus musculus (house mouse) ]

    Gene ID: 77595, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Nup210lprovided by MGI
    Official Full Name
    nucleoporin 210-likeprovided by MGI
    Primary source
    MGI:MGI:1924845
    See related
    Ensembl:ENSMUSG00000027939 AllianceGenome:MGI:1924845
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    R26-EGFP; 4930548O11Rik; Tg(Gt(ROSA)26Sor-EGFP)130910Eps
    Summary
    Acts upstream of or within Sertoli cell development and spermatid development. Predicted to be located in membrane. Predicted to be part of nuclear pore. Orthologous to human NUP210L (nucleoporin 210 like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 14.1) and CNS E11.5 (RPKM 0.7) See more
    Orthologs
    human all
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    Genomic context

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    See Nup210l in Genome Data Viewer
    Location:
    3 F1; 3 39.2 cM
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (90011445..90119458)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (90101007..90212151)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_08271 Neighboring gene STARR-positive B cell enhancer ABC_E3447 Neighboring gene STARR-positive B cell enhancer ABC_E7923 Neighboring gene microRNA 190b Neighboring gene STARR-seq mESC enhancer starr_08272 Neighboring gene tropomyosin 3, gamma Neighboring gene predicted gene, 34865 Neighboring gene predicted gene, 23723 Neighboring gene STARR-seq mESC enhancer starr_08276 Neighboring gene predicted gene, 24185 Neighboring gene STARR-positive B cell enhancer ABC_E1624 Neighboring gene ribosomal protein S27 Neighboring gene RAB13, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Spermatozoa in mice lacking the nucleoporin NUP210L show defects in head shape and motility but not in nuclear compaction or histone replacement. Al Dala Ali M, et al. Clin Genet, 2024 Apr. PMID 38129135
    2. Ubiquitous expression of marker transgenes in mice and rats. Kisseberth WC, et al. Dev Biol, 1999 Oct 1. PMID 10491262
    3. Mutational insertion of a ROSA26-EGFP transgene leads to defects in spermiogenesis and male infertility in mice. Walters EM, et al. Comp Med, 2009 Dec. PMID 20034429, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Spermatozoa in mice lacking the nucleoporin NUP210L show defects in head shape and motility but not in nuclear compaction or histone replacement.
      Title: Spermatozoa in mice lacking the nucleoporin NUP210L show defects in head shape and motility but not in nuclear compaction or histone replacement.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within Sertoli cell development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nuclear pore membrane glycoprotein 210-like
    Names
    nucleoporin 210 kDa-like
    nucleoporin Nup210-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029937.2 → NP_084213.1  nuclear pore membrane glycoprotein 210-like precursor

      See identical proteins and their annotated locations for NP_084213.1

      Status: VALIDATED

      Source sequence(s)
      AC119825, AC121963, AC163616
      Consensus CDS
      CCDS50969.1
      UniProtKB/Swiss-Prot
      Q9D2F7
      UniProtKB/TrEMBL
      A0A0G2JFZ8
      Related
      ENSMUSP00000029548.5, ENSMUST00000029548.9
      Conserved Domains (2) summary
      pfam02368
      Location:1079 → 1153
      Big_2; Bacterial Ig-like domain (group 2)
      cl02708
      Location:476 → 523
      Big_2; Bacterial Ig-like domain (group 2)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      90011445..90119458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D2F7.2 GenPept UniProtKB/Swiss-Prot:Q9D2F7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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