Spag9 sperm associated antigen 9 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Spag9provided by MGI
Official Full Name: sperm associated antigen 9provided by MGI
Primary source: MGI:MGI:1918084
See related: Ensembl:ENSMUSG00000020859 AllianceGenome:MGI:1918084
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: JLP; Jip4; syd1; JIP-4; JSAP2; JSAP2a; Mapk8ip4; 3110018C07Rik; 4733401I23Rik; 4831406C20Rik
Summary: Enables several functions, including JUN kinase binding activity; MAP-kinase scaffold activity; and kinesin binding activity. Acts upstream of or within positive regulation of MAPK cascade; positive regulation of neuron differentiation; and striated muscle cell differentiation. Located in cytoplasm. Is expressed in central nervous system; dorsal root ganglion; retina; and trigeminal nerve. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Orthologous to human SPAG9 (sperm associated antigen 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in CNS E18 (RPKM 26.0), cerebellum adult (RPKM 26.0) and 26 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 D; 11 58.9 cM

Exon count:: 35

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (93886794..94016919)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (93996046..94126093)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A negative feedback loop between JNK-associated leucine zipper protein and TGF-beta1 regulates kidney fibrosis.
Title: A negative feedback loop between JNK-associated leucine zipper protein and TGF-β1 regulates kidney fibrosis.
JLP-deficiency impaired T-cell proliferation.
Title: Scaffold protein JLP mediates TCR-initiated CD4(+)T cell activation and CD154 expression.
data establish JSAP1 and JLP as positive regulators of kinesin-1-dependent axonal transport, which prevents neuronal degeneration.
Title: JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration.
JSAP1 and JLP play critical roles in kinesin-1-dependent axonal transport
Title: Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice.
JSAP1 and JLP, which might be paralogous to each other, are critical and functionally redundant in cytokinesis and control ARF6 localization to the midbody by forming a tripartite complex of JSAP1/JLP, active ARF6, and kinesin-1.
Title: JSAP1 and JLP are required for ARF6 localization to the midbody in cytokinesis.
JLP in skin basal keratinocytes plays an important role in UVB-induced apoptosis by modulating p38 MAPK signaling pathways.
Title: The scaffold protein JLP plays a key role in regulating ultraviolet B-induced apoptosis in mice.
Data indicate a role of a scaffolding protein JLP in the regulation of surface CD40 expression and fine-tuning of dendritic cell (DC) function.
Title: A novel role of the scaffolding protein JLP in tuning CD40-induced activation of dendritic cells.
A functional role for JLP in the gep oncogene-regulated neoplastic signaling pathway.
Title: Neoplastic transformation induced by the gep oncogenes involves the scaffold protein JNK-interacting leucine zipper protein.
Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
Title: Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
Ablation of the scaffold protein JLP causes reduced fertility in male mice.
Title: Ablation of the scaffold protein JLP causes reduced fertility in male mice.

Submit: New GeneRIF Correction See all GeneRIFs (14)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Chemically induced (ENU) (1)
Endonuclease-mediated (3)
Targeted (2) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH126691 (e-PCR)
- UniSTS:209728

C76628 (e-PCR)
- UniSTS:180294

AW552012 (e-PCR)
- UniSTS:180295

AA925269 (e-PCR)
- UniSTS:261749

NoName (e-PCR)
- UniSTS:236710

AA925269 (e-PCR)
- UniSTS:243381

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables JUN kinase binding	IBA Inferred from Biological aspect of Ancestor more info
enables JUN kinase binding	IDA Inferred from Direct Assay more info	PubMed
enables MAP-kinase scaffold activity	IBA Inferred from Biological aspect of Ancestor more info
enables MAP-kinase scaffold activity	IDA Inferred from Direct Assay more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables kinesin binding	IBA Inferred from Biological aspect of Ancestor more info
enables kinesin binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables signaling receptor complex adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in MAPK cascade	IEA Inferred from Electronic Annotation more info
involved_in lysosome localization	ISO Inferred from Sequence Orthology more info
involved_in lysosome localization	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of dendrite extension	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of dendrite extension	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of neuron differentiation	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of neuron differentiation	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of protein phosphorylation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of MAPK cascade	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of MAPK cascade	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of cell migration	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of cell migration	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of neuron differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within retrograde transport, endosome to Golgi	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within striated muscle cell differentiation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in centriolar satellite	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in cytosol	TAS Traceable Author Statement more info
located_in lysosomal membrane	ISO Inferred from Sequence Orthology more info
located_in lysosomal membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: C-Jun-amino-terminal kinase-interacting protein 4

Names: JNK-associated leucine-zipper protein; JNK-interacting leucine zipper; JNK-interacting protein 4; JNK/SAPK-associated protein 2; mitogen-activated protein kinase 8-interacting protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025428.2 → NP_001020599.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 2

Status: VALIDATED

Source sequence(s)

AK014060, BC052058, BC094670, CJ123181, CK781075, CO044222

Consensus CDS

CCDS36282.1

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

UniProtKB/TrEMBL

E9PUD1

Related

ENSMUSP00000090452.5, ENSMUST00000092777.11

Conserved Domains (2) summary

pfam15898
Location:301 → 400

PRKG1_interact; cGMP-dependent protein kinase interacting domain

pfam16471
Location:254 → 322

JIP_LZII; JNK-interacting protein leucine zipper II
NM_001025429.2 → NP_001020600.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 3

Status: VALIDATED

Source sequence(s)

AK014060, AK172961, BC094670, CJ123181, CO044222

Consensus CDS

CCDS56797.1

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Related

ENSMUSP00000075115.7, ENSMUST00000075695.13

Conserved Domains (2) summary

pfam15898
Location:300 → 399

PRKG1_interact; cGMP-dependent protein kinase interacting domain

pfam16471
Location:253 → 321

JIP_LZII; JNK-interacting protein leucine zipper II
NM_001025430.2 → NP_001020601.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 4

See identical proteins and their annotated locations for NP_001020601.1

Status: VALIDATED

Source sequence(s)

AK014060, BC094670, CJ123181, CO044222

Consensus CDS

CCDS25249.1

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

UniProtKB/TrEMBL

A0A0R4J196

Related

ENSMUSP00000099457.4, ENSMUST00000103168.10

Conserved Domains (2) summary

pfam15898
Location:296 → 395

PRKG1_interact; cGMP-dependent protein kinase interacting domain

pfam16471
Location:249 → 317

JIP_LZII; JNK-interacting protein leucine zipper II
NM_001199203.2 → NP_001186132.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 5

Status: VALIDATED

Source sequence(s)

AB047782, AK147431, AK161623, AL662838, CO044222

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (4) summary

pfam07926
Location:56 → 162

TPR_MLP1_2; TPR/MLP1/MLP2-like protein

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam15898
Location:453 → 552

PRKG1_interact; cGMP-dependent protein kinase interacting domain

pfam16471
Location:406 → 474

JIP_LZII; JNK-interacting protein leucine zipper II
NM_001199204.2 → NP_001186133.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 6

See identical proteins and their annotated locations for NP_001186133.1

Status: VALIDATED

Source sequence(s)

AK147431, AK161623, CO044222, FJ042496

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

UniProtKB/TrEMBL

B8X349

Conserved Domains (4) summary

pfam07926
Location:56 → 162

TPR_MLP1_2; TPR/MLP1/MLP2-like protein

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam15898
Location:439 → 538

PRKG1_interact; cGMP-dependent protein kinase interacting domain

pfam16471
Location:392 → 460

JIP_LZII; JNK-interacting protein leucine zipper II
NM_001199205.2 → NP_001186134.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 7

Status: VALIDATED

Source sequence(s)

AK147431, BC060100, CJ123181, CO044222

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (2) summary

pfam15898
Location:296 → 395

PRKG1_interact; cGMP-dependent protein kinase interacting domain

pfam16471
Location:249 → 317

JIP_LZII; JNK-interacting protein leucine zipper II
NM_001363157.1 → NP_001350086.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 8

Status: VALIDATED

Source sequence(s)

AL662838

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (3) summary

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam16471
Location:396 → 464

JIP_LZII; JNK-interacting protein leucine zipper II

cl25732
Location:33 → 520

SMC_N; RecF/RecN/SMC N terminal domain
NM_027569.3 → NP_081845.2 C-Jun-amino-terminal kinase-interacting protein 4 isoform 1

Status: VALIDATED

Source sequence(s)

AF327451, AK030165, AK172961, BB618351, BC060506, BC094670, CO044222

Consensus CDS

CCDS25248.1

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Related

ENSMUSP00000042271.8, ENSMUST00000041956.14

Conserved Domains (4) summary

pfam07926
Location:56 → 162

TPR_MLP1_2; TPR/MLP1/MLP2-like protein

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam15898
Location:439 → 538

PRKG1_interact; cGMP-dependent protein kinase interacting domain

pfam16471
Location:392 → 460

JIP_LZII; JNK-interacting protein leucine zipper II

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000077.7 Reference GRCm39 C57BL/6J

Range

93886794..94016919

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006534210.5 → XP_006534273.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X1

See identical proteins and their annotated locations for XP_006534273.1

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (4) summary

COG0419
Location:22 → 539

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam16471
Location:415 → 483

JIP_LZII; JNK-interacting protein leucine zipper II

pfam17380
Location:458 → 651

DUF5401; Family of unknown function (DUF5401)
XM_006534214.5 → XP_006534277.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X5

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (4) summary

COG0419
Location:22 → 539

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam16471
Location:415 → 483

JIP_LZII; JNK-interacting protein leucine zipper II

pfam17380
Location:458 → 651

DUF5401; Family of unknown function (DUF5401)
XM_006534212.5 → XP_006534275.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X3

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (4) summary

COG0419
Location:22 → 534

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam16471
Location:410 → 478

JIP_LZII; JNK-interacting protein leucine zipper II

pfam17380
Location:453 → 646

DUF5401; Family of unknown function (DUF5401)
XM_006534211.5 → XP_006534274.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X2

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (4) summary

COG0419
Location:22 → 535

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam16471
Location:411 → 479

JIP_LZII; JNK-interacting protein leucine zipper II

pfam17380
Location:454 → 647

DUF5401; Family of unknown function (DUF5401)
XM_006534213.5 → XP_006534276.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X4

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (4) summary

COG0419
Location:22 → 530

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam16471
Location:406 → 474

JIP_LZII; JNK-interacting protein leucine zipper II

pfam17380
Location:449 → 642

DUF5401; Family of unknown function (DUF5401)
XM_006534215.5 → XP_006534278.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X6

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (4) summary

COG0419
Location:22 → 525

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

pfam09744
Location:25 → 178

Jnk-SapK_ap_N; JNK_SAPK-associated protein-1

pfam16471
Location:401 → 469

JIP_LZII; JNK-interacting protein leucine zipper II

pfam17380
Location:444 → 637

DUF5401; Family of unknown function (DUF5401)
XM_030246314.2 → XP_030102174.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X11

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (2) summary

COG1196
Location:252 → 398

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam16471
Location:250 → 318

JIP_LZII; JNK-interacting protein leucine zipper II
XM_030246315.2 → XP_030102175.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X12

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (3) summary

COG1196
Location:238 → 384

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

TIGR04523
Location:129 → 316

Mplasa_alph_rch; helix-rich Mycoplasma protein

pfam16471
Location:236 → 304

JIP_LZII; JNK-interacting protein leucine zipper II
XM_030246317.2 → XP_030102177.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X13

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (3) summary

COG1196
Location:229 → 375

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

TIGR04523
Location:129 → 307

Mplasa_alph_rch; helix-rich Mycoplasma protein

pfam16471
Location:227 → 295

JIP_LZII; JNK-interacting protein leucine zipper II
XM_030246318.2 → XP_030102178.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X14

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (3) summary

COG1196
Location:229 → 375

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

TIGR04523
Location:129 → 307

Mplasa_alph_rch; helix-rich Mycoplasma protein

pfam16471
Location:227 → 295

JIP_LZII; JNK-interacting protein leucine zipper II
XM_006534216.5 → XP_006534279.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X7

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (3) summary

COG1196
Location:274 → 420

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

TIGR04523
Location:165 → 352

Mplasa_alph_rch; helix-rich Mycoplasma protein

pfam16471
Location:272 → 340

JIP_LZII; JNK-interacting protein leucine zipper II
XM_030246313.2 → XP_030102173.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X8

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (3) summary

COG1196
Location:265 → 411

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

TIGR04523
Location:165 → 343

Mplasa_alph_rch; helix-rich Mycoplasma protein

pfam16471
Location:263 → 331

JIP_LZII; JNK-interacting protein leucine zipper II
XM_006534217.5 → XP_006534280.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X9

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (3) summary

COG1196
Location:260 → 406

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

TIGR04523
Location:151 → 338

Mplasa_alph_rch; helix-rich Mycoplasma protein

pfam16471
Location:258 → 326

JIP_LZII; JNK-interacting protein leucine zipper II
XM_006534218.5 → XP_006534281.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform X10

UniProtKB/Swiss-Prot

Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2

Conserved Domains (2) summary

COG1196
Location:220 → 401

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam16471
Location:253 → 321

JIP_LZII; JNK-interacting protein leucine zipper II