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    SLC18A2 solute carrier family 18 member A2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701133, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SLC18A2provided by VGNC
    Official Full Name
    solute carrier family 18 member A2provided by VGNC
    Primary source
    VGNC:VGNC:77407
    See related
    Ensembl:ENSMMUG00000014817
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    VMAT2
    Orthologs
    human mouse all
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    Genomic context

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    See SLC18A2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (117717367..117756390)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (113143480..113182652)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene potassium two pore domain channel subfamily K member 18 Neighboring gene uncharacterized LOC114670043 Neighboring gene uncharacterized LOC114670044 Neighboring gene PDZ domain containing 8 Neighboring gene uncharacterized LOC107000293 Neighboring gene uncharacterized LOC107000294

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Decreased vesicular monoamine transporter type 2 availability in the striatum following chronic cocaine self-administration in nonhuman primates. Narendran R, et al. Biol Psychiatry, 2015 Mar 1. PMID 25062684, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. these results in rhesus monkey clearly demonstrated a reduction in VMAT2 binding in the striatum following prolonged exposure to cocaine.
      Title: Decreased vesicular monoamine transporter type 2 availability in the striatum following chronic cocaine self-administration in nonhuman primates.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serotonin:sodium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in aminergic neurotransmitter loading into synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in synaptic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in terminal bouton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    synaptic vesicular amine transporter
    Names
    solute carrier family 18 (vesicular monoamine), member 2
    vesicle monoamine transporter type 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      117717367..117756390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028826907.1 → XP_028682740.1  synaptic vesicular amine transporter

      UniProtKB/TrEMBL
      A0A1D5QT69, A0A5S6RC33, A0A8J8Y0S9, G7N180
      Related
      ENSMMUP00000051248.2, ENSMMUT00000070556.2
      Conserved Domains (1) summary
      cd17384
      Location:126 → 474
      MFS_SLC18A1_2_VAT1_2; Vesicular amine transporters 1 (VAT1) and 2 (VAT2), and similar transporters of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials