BLB1 major histocompatibility complex Y, class II beta BLB1 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: BLB1provided by CGNC
Official Full Name: major histocompatibility complex Y, class II beta BLB1provided by CGNC
Primary source: CGNC:54366
See related: Ensembl:ENSGALG00010002991
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: B-LB; B-LB21; GSP-BLB1
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Genomic context

Location:: chromosome: 16

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	16	NC_052547.1 (2185532..2187356, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	16	NC_052588.1 (1086656..1088481, complement)

Chromosome 16 - NC_052547.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables MHC class II protein complex binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immunoglobulin production involved in immunoglobulin-mediated immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptide antigen assembly with MHC class II protein complex	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T cell activation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of MHC class II protein complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: Major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain); major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain)

Names: B-L beta minor; BLB major; Bl-Beta II protein; MHC class II B-L beta chain; MHC class II antigen B-F minor heavy chain; MHC class II antigen beta chain; MHC class II beta 1 domain; MHC class II beta chain 1; Major histocompatibility complex class II beta chain BLB1; major histocompatibility complex class II B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001044679.2 → NP_001038144.2 Major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain) precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000283

UniProtKB/TrEMBL

A0A1D5PLI8

Related

ENSGALP00010004246.1, ENSGALT00010006984.1

Conserved Domains (2) summary

cd05766
Location:123 → 216

IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain

pfam00969
Location:39 → 113

MHC_II_beta; Class II histocompatibility antigen, beta domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052547.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

2185532..2187356 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015294994.4 → XP_015150480.1 major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain) isoform X1

UniProtKB/TrEMBL

A0A1D5P3L9, A5HUL2, B5BSJ6, B6RCP2, F1C6U2, F1NSZ6

Related

ENSGALP00010004245.1, ENSGALT00010006982.1

Conserved Domains (2) summary

cd05766
Location:123 → 216

IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain

pfam00969
Location:39 → 113

MHC_II_beta; Class II histocompatibility antigen, beta domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052588.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

1086656..1088481 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046928562.1 → XP_046784518.1 major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain) isoform X1

UniProtKB/TrEMBL

A0A1D5P3L9, A5HUL2, F1NSZ6