Krt42 keratin 42 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Krt42provided by MGI
Official Full Name: keratin 42provided by MGI
Primary source: MGI:MGI:1915489
See related: Ensembl:ENSMUSG00000053654 AllianceGenome:MGI:1915489
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: K42; K17n; Ka22; CK-42; ecat6; 2410039E07Rik
Summary: Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in cytoplasm and intermediate filament. Predicted to be active in keratin filament. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver; and lung. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 11 D; 11 63.44 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (100153708..100160777, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (100262882..100269951, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in epithelial cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in intermediate filament organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in intermediate filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin, type I cytoskeletal 42

Names: cytokeratin-42; keratin 17n; predicted ortholog of type I keratin KA22; type I keratin KA22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212483.3 → NP_997648.2 keratin, type I cytoskeletal 42

See identical proteins and their annotated locations for NP_997648.2

Status: VALIDATED

Source sequence(s)

AL590873

Consensus CDS

CCDS25416.1

UniProtKB/Swiss-Prot

A7MAW4, Q2M1G8, Q6IFX2, Q6SEK1

Related

ENSMUSP00000017270.7, ENSMUST00000017270.8

Conserved Domains (2) summary

pfam00038
Location:93 → 404

Filament; Intermediate filament protein

pfam07195
Location:236 → 358

FliD_C; Flagellar hook-associated protein 2 C-terminus