Lipf lipase, gastric [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Lipfprovided by MGI
Official Full Name: lipase, gastricprovided by MGI
Primary source: MGI:MGI:1914967
See related: Ensembl:ENSMUSG00000024768 AllianceGenome:MGI:1914967
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2310051B21Rik
Summary: Predicted to enable triacylglycerol lipase activity. Predicted to be involved in lipid catabolic process and malate metabolic process. Predicted to be located in extracellular region and mitochondrion. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in body wall mesenchyme. Orthologous to human LIPF (lipase F, gastric type). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in testis adult (RPKM 2.3), genital fat pad adult (RPKM 0.6) and 3 other tissues See more
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Genomic context

Location:: 19 C1; 19 29.29 cM

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (33938648..33954213)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (33961248..33976813)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

General gene information

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Markers

Lipf (e-PCR), detects polymorphism
- UniSTS:546845

AV082900 (e-PCR)
- UniSTS:164655

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables malate dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables triacylglycerol lipase activity	IBA Inferred from Biological aspect of Ancestor more info
enables triacylglycerol lipase activity	ISO Inferred from Sequence Orthology more info
enables triacylglycerol lipase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in lipid catabolic process	IEA Inferred from Electronic Annotation more info
involved_in malate metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: gastric triacylglycerol lipase

Names: GL; gastric lipase

NP_080610.1

EC 3.1.1.3

XP_017173769.1

EC 3.1.1.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.