Pyurf Pigy upstream reading frame [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Pyurfprovided by MGI
Official Full Name: Pigy upstream reading frameprovided by MGI
Primary source: MGI:MGI:1913709
See related: Ensembl:ENSMUSG00000043162 AllianceGenome:MGI:1913709
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Prey; 2610022G08Rik
Summary: This gene encodes a small protein with a conserved DUF343 domain. The human ortholog of this gene expresses two distinct proteins from upstream and downstream coding regions. The upstream CDS encoding a DUF343 domain-containing protein has been conserved at this mouse locus, but the downstream CDS encoding a subunit of an enzyme involved in glycosylphosphatidylinositol biosynthesis has not been conserved. Instead, a separate locus on mouse chromosome 9 encodes the mouse homolog of the human phosphatidylinositol glycan anchor biosynthesis, class Y protein. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in adrenal adult (RPKM 13.8), mammary gland adult (RPKM 6.6) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 6 B3; 6 27.82 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (57661724..57669063, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (57684739..57692078, complement)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)

General gene information

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Markers

D6Mit317 (e-PCR), detects polymorphism
- UniSTS:130870

AI847956 (e-PCR)
- UniSTS:179380

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
acts_upstream_of_or_within GPI anchor biosynthetic process	ISA Inferred from Sequence Alignment more info	PubMed
involved_in protein stabilization	ISO Inferred from Sequence Orthology more info
involved_in protein stabilization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	ISA Inferred from Sequence Alignment more info	PubMed
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	ISA Inferred from Sequence Alignment more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISA Inferred from Sequence Alignment more info	PubMed

General protein information

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Preferred Names: protein preY, mitochondrial

Names: pre-Y homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.