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    Defb30 defensin beta 30 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 641656, updated on 2-Nov-2024

    Summary

    Official Symbol
    Defb30provided by RGD
    Official Full Name
    defensin beta 30provided by RGD
    Primary source
    RGD:1559641
    See related
    EnsemblRapid:ENSRNOG00000038758 AllianceGenome:RGD:1559641
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. Orthologous to human DEFB135 (defensin beta 135). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 1.5) See more
    Orthologs
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    Genomic context

    See Defb30 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (41470697..41474458, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (37294713..37298474, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (46220136..46223429, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene defensin beta 41 Neighboring gene defensin beta 43 Neighboring gene defensin beta 44 Neighboring gene cathepsin B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    beta-defensin 30
    Names
    BD-30

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037531.2NP_001032620.1  beta-defensin 30 precursor

      See identical proteins and their annotated locations for NP_001032620.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/Swiss-Prot
      Q32ZG2
      Related
      ENSRNOP00000055981.2, ENSRNOT00000059211.5
      Conserved Domains (1) summary
      pfam13841
      Location:3463
      Defensin_beta_2; Beta defensin
    2. NM_001412584.1NP_001399513.1  beta-defensin 30 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/Swiss-Prot
      Q32ZG2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      41470697..41474458 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)