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    Sdf2l1 stromal cell-derived factor 2-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 64136, updated on 2-Nov-2024

    Summary

    Official Symbol
    Sdf2l1provided by MGI
    Official Full Name
    stromal cell-derived factor 2-like 1provided by MGI
    Primary source
    MGI:MGI:2149842
    See related
    Ensembl:ENSMUSG00000022769 AllianceGenome:MGI:2149842
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable ATPase binding activity; misfolded protein binding activity; and protein-folding chaperone binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to act upstream of or within ERAD pathway; cellular response to misfolded protein; and regulation of apoptotic process. Part of endoplasmic reticulum chaperone complex. Is expressed in ventricular layer. Orthologous to human SDF2L1 (stromal cell derived factor 2 like 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 56.1), colon adult (RPKM 48.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Sdf2l1 in Genome Data Viewer
    Location:
    16 A3; 16 10.62 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (16948002..16950247, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (17130138..17132383, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2610318N02 gene Neighboring gene STARR-positive B cell enhancer ABC_E9927 Neighboring gene microRNA 130b Neighboring gene microRNA 301b Neighboring gene STARR-positive B cell enhancer ABC_E7429 Neighboring gene STARR-positive B cell enhancer ABC_E214 Neighboring gene Rps20 pseudogene Neighboring gene coiled-coil domain containing 116 Neighboring gene STARR-positive B cell enhancer ABC_E4157 Neighboring gene YdjC homolog (bacterial)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATPase binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables misfolded protein binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables protein-folding chaperone binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    part_of endoplasmic reticulum chaperone complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum lumen IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    part_of protein folding chaperone complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein folding chaperone complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    stromal cell-derived factor 2-like protein 1
    Names
    SDF2-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022324.3NP_071719.1  stromal cell-derived factor 2-like protein 1 precursor

      See identical proteins and their annotated locations for NP_071719.1

      Status: VALIDATED

      Source sequence(s)
      BC053425, BY253823
      Consensus CDS
      CCDS37270.1
      UniProtKB/Swiss-Prot
      Q9ESP1, Q9ESP2
      Related
      ENSMUSP00000023453.8, ENSMUST00000023453.10
      Conserved Domains (2) summary
      smart00472
      Location:95150
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      cl19745
      Location:159201
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      16948002..16950247 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)