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    LRRC4 leucine rich repeat containing 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 607997, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LRRC4provided by VGNC
    Official Full Name
    leucine rich repeat containing 4provided by VGNC
    Primary source
    VGNC:VGNC:42797
    See related
    Ensembl:ENSCAFG00845025632
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LRRC4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (8090773..8094337)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (8010280..8013846)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (8182826..8186395)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (8295211..8298775)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (8035990..8039549)

    Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866729 Neighboring gene uncharacterized LOC119866555 Neighboring gene uncharacterized LOC111098732 Neighboring gene staphylococcal nuclease and tudor domain containing 1 Neighboring gene 40S ribosomal protein S8-like Neighboring gene complex III assembly factor LYRM7-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in excitatory synapse assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in modulation of chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in postsynaptic density protein 95 clustering IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic membrane adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051818.1 Reference ROS_Cfam_1.0

      Range
      8090773..8094337
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038686229.1 → XP_038542157.1  leucine-rich repeat-containing protein 4

      UniProtKB/TrEMBL
      A0A8C0LAK3, A0A8C0MTE6, A0A8I3PVC0, A0A8P0PMQ4
      Related
      ENSCAFP00845035471.1, ENSCAFT00845045237.1
      Conserved Domains (7) summary
      smart00013
      Location:45 → 78
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:299 → 350
      LRRCT; Leucine rich repeat C-terminal domain
      smart00410
      Location:358 → 440
      IG_like; Immunoglobulin like
      COG4886
      Location:73 → 290
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:76 → 99
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:74 → 132
      LRR_8; Leucine rich repeat
      cd00096
      Location:352 → 355
      Ig; Ig strand A [structural motif]

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049274.1 Alternate UMICH_Zoey_3.1

      Range
      8295211..8298775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038494314.1 → XP_038350242.1  leucine-rich repeat-containing protein 4

      Conserved Domains (7) summary
      smart00013
      Location:45 → 78
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:299 → 350
      LRRCT; Leucine rich repeat C-terminal domain
      smart00410
      Location:358 → 440
      IG_like; Immunoglobulin like
      COG4886
      Location:73 → 290
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:76 → 99
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:74 → 132
      LRR_8; Leucine rich repeat
      cd00096
      Location:352 → 355
      Ig; Ig strand A [structural motif]

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

      Range
      8035990..8039549
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038620540.1 → XP_038476468.1  leucine-rich repeat-containing protein 4

      Conserved Domains (7) summary
      smart00013
      Location:45 → 78
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:299 → 350
      LRRCT; Leucine rich repeat C-terminal domain
      smart00410
      Location:358 → 440
      IG_like; Immunoglobulin like
      COG4886
      Location:73 → 290
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:76 → 99
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:74 → 132
      LRR_8; Leucine rich repeat
      cd00096
      Location:352 → 355
      Ig; Ig strand A [structural motif]

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

      Range
      8182826..8186395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038556611.1 → XP_038412539.1  leucine-rich repeat-containing protein 4

      UniProtKB/TrEMBL
      A0A8C0LAK3, A0A8C0MTE6, A0A8I3PVC0, A0A8P0PMQ4
      Conserved Domains (7) summary
      smart00013
      Location:45 → 78
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:299 → 350
      LRRCT; Leucine rich repeat C-terminal domain
      smart00410
      Location:358 → 440
      IG_like; Immunoglobulin like
      COG4886
      Location:73 → 290
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:76 → 99
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:74 → 132
      LRR_8; Leucine rich repeat
      cd00096
      Location:352 → 355
      Ig; Ig strand A [structural motif]

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      8010280..8013846
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_844368.6 → XP_849461.1  leucine-rich repeat-containing protein 4

      See identical proteins and their annotated locations for XP_849461.1

      UniProtKB/TrEMBL
      A0A8C0LAK3, A0A8C0MTE6, A0A8I3PVC0, A0A8P0PMQ4
      Conserved Domains (7) summary
      smart00013
      Location:45 → 78
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:299 → 350
      LRRCT; Leucine rich repeat C-terminal domain
      smart00410
      Location:358 → 440
      IG_like; Immunoglobulin like
      COG4886
      Location:73 → 290
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:76 → 99
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:74 → 132
      LRR_8; Leucine rich repeat
      cd00096
      Location:352 → 355
      Ig; Ig strand A [structural motif]
    Nucleotide Protein
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