U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    GCK glucokinase [ Canis lupus familiaris (dog) ]

    Gene ID: 606490, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GCKprovided by VGNC
    Official Full Name
    glucokinaseprovided by VGNC
    Primary source
    VGNC:VGNC:111508
    See related
    Ensembl:ENSCAFG00845013118
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GCK in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 16 NC_051820.1 (14737904..14781009)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 16 NC_006598.4 (2080944..2123987, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 16 NC_049237.1 (14349631..14392705)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 16 NC_049757.1 (14369169..14412232)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) Unplaced Scaffold NW_023332296.1 (758331..801402)

    Chromosome 16 - NC_051820.1Genomic Context describing neighboring genes Neighboring gene calcium/calmodulin dependent protein kinase II beta Neighboring gene uncharacterized LOC119869528 Neighboring gene YKT6 v-SNARE homolog Neighboring gene uncharacterized LOC119869537 Neighboring gene myosin light chain 7 Neighboring gene DNA polymerase delta 2, accessory subunit

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables D-glucose binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fructokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glucokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mannokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glucose 6-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular glucose homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of insulin secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    hexokinase-4
    Names
    glucokinase (hexokinase 4)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051820.1 Reference ROS_Cfam_1.0

      Range
      14737904..14781009
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038689301.1 → XP_038545229.1  hexokinase-4 isoform X2

      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    2. XM_038689300.1 → XP_038545228.1  hexokinase-4 isoform X2

      Related
      ENSCAFP00845018333.1, ENSCAFT00845023360.1
      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    3. XM_038689302.1 → XP_038545230.1  hexokinase-4 isoform X3

      Conserved Domains (2) summary
      pfam00349
      Location:3 → 191
      Hexokinase_1
      pfam03727
      Location:197 → 313
      Hexokinase_2

    4. XM_038689299.1 → XP_038545227.1  hexokinase-4 isoform X1

      Related
      ENSCAFP00845018350.1, ENSCAFT00845023382.1
      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 338
      Hexokinase_2

    5. XM_038689303.1 → XP_038545231.1  hexokinase-4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0KSU5, A0A8I3NNP9
      Related
      ENSCAFP00845018396.1, ENSCAFT00845023439.1
      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 456
      Hexokinase_2

    6. XM_038689304.1 → XP_038545232.1  hexokinase-4 isoform X5

      Conserved Domains (1) summary
      pfam03727
      Location:14 → 158
      Hexokinase_2

    7. XM_038689305.1 → XP_038545233.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    8. XM_038689306.1 → XP_038545234.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NW_023332296.1 Alternate UMICH_Zoey_3.1

      Range
      758331..801402
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038525235.1 → XP_038381163.1  hexokinase-4 isoform X2

      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    2. XM_038525234.1 → XP_038381162.1  hexokinase-4 isoform X2

      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    3. XM_038525236.1 → XP_038381164.1  hexokinase-4 isoform X3

      Conserved Domains (2) summary
      pfam00349
      Location:3 → 191
      Hexokinase_1
      pfam03727
      Location:197 → 313
      Hexokinase_2

    4. XM_038525233.1 → XP_038381161.1  hexokinase-4 isoform X1

      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 338
      Hexokinase_2

    5. XM_038525237.1 → XP_038381165.1  hexokinase-4 isoform X4

      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 456
      Hexokinase_2

    6. XM_038525238.1 → XP_038381166.1  hexokinase-4 isoform X5

      Conserved Domains (1) summary
      pfam03727
      Location:14 → 158
      Hexokinase_2

    7. XM_038525239.1 → XP_038381167.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    8. XM_038525240.1 → XP_038381168.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049757.1 Alternate UNSW_CanFamBas_1.0

      Range
      14369169..14412232
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038623564.1 → XP_038479492.1  hexokinase-4 isoform X2

      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    2. XM_038623563.1 → XP_038479491.1  hexokinase-4 isoform X2

      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    3. XM_038623565.1 → XP_038479493.1  hexokinase-4 isoform X3

      Conserved Domains (2) summary
      pfam00349
      Location:3 → 191
      Hexokinase_1
      pfam03727
      Location:197 → 313
      Hexokinase_2

    4. XM_038623562.1 → XP_038479490.1  hexokinase-4 isoform X1

      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 338
      Hexokinase_2

    5. XM_038623566.1 → XP_038479494.1  hexokinase-4 isoform X4

      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 456
      Hexokinase_2

    6. XM_038623567.1 → XP_038479495.1  hexokinase-4 isoform X5

      Conserved Domains (1) summary
      pfam03727
      Location:14 → 158
      Hexokinase_2

    7. XM_038623568.1 → XP_038479496.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    8. XM_038623569.1 → XP_038479497.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049237.1 Alternate UU_Cfam_GSD_1.0

      Range
      14349631..14392705
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038559568.1 → XP_038415496.1  hexokinase-4 isoform X2

      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    2. XM_038559567.1 → XP_038415495.1  hexokinase-4 isoform X2

      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    3. XM_038559569.1 → XP_038415497.1  hexokinase-4 isoform X3

      Conserved Domains (2) summary
      pfam00349
      Location:3 → 191
      Hexokinase_1
      pfam03727
      Location:197 → 313
      Hexokinase_2

    4. XM_038559566.1 → XP_038415494.1  hexokinase-4 isoform X1

      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 338
      Hexokinase_2

    5. XM_038559570.1 → XP_038415498.1  hexokinase-4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0KSU5, A0A8I3NNP9
      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 456
      Hexokinase_2

    6. XM_038559571.1 → XP_038415499.1  hexokinase-4 isoform X5

      Conserved Domains (1) summary
      pfam03727
      Location:14 → 158
      Hexokinase_2

    7. XM_038559572.1 → XP_038415500.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    8. XM_038559573.1 → XP_038415501.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006598.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      2080944..2123987 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038452450.1 → XP_038308378.1  hexokinase-4 isoform X2

      Conserved Domains (2) summary
      pfam00349
      Location:15 → 215
      Hexokinase_1
      pfam03727
      Location:221 → 337
      Hexokinase_2

    2. XM_038452452.1 → XP_038308380.1  hexokinase-4 isoform X3

      Conserved Domains (2) summary
      pfam00349
      Location:3 → 191
      Hexokinase_1
      pfam03727
      Location:197 → 313
      Hexokinase_2

    3. XM_038452449.1 → XP_038308377.1  hexokinase-4 isoform X1

      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 338
      Hexokinase_2

    4. XM_038452453.1 → XP_038308381.1  hexokinase-4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0KSU5, A0A8I3NNP9
      Conserved Domains (2) summary
      pfam00349
      Location:18 → 216
      Hexokinase_1
      pfam03727
      Location:222 → 456
      Hexokinase_2

    5. XM_038452454.1 → XP_038308382.1  hexokinase-4 isoform X5

      Conserved Domains (1) summary
      pfam03727
      Location:14 → 158
      Hexokinase_2

    6. XM_038452455.1 → XP_038308383.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2

    7. XM_038452456.1 → XP_038308384.1  hexokinase-4 isoform X6

      Conserved Domains (1) summary
      pfam03727
      Location:1 → 75
      Hexokinase_2
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.