Akap14 A-kinase anchoring protein 14 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Akap14provided by RGD
Official Full Name: A-kinase anchoring protein 14provided by RGD
Primary source: RGD:708510
See related: EnsemblRapid:ENSRNOG00000006899 AllianceGenome:RGD:708510
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Enables protein kinase A binding activity. Involved in spermatogenesis. Located in sperm fibrous sheath. Orthologous to human AKAP14 (A-kinase anchoring protein 14). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Testes (RPKM 22.8), Lung (RPKM 8.5) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq35

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (121261195..121276376, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (116395512..116410697, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (123773430..123788898, complement)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein kinase A binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase A regulatory subunit binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein kinase A regulatory subunit binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in spermatogenesis	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in axoneme	ISO Inferred from Sequence Orthology more info
part_of cAMP-dependent protein kinase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of cAMP-dependent protein kinase complex	ISO Inferred from Sequence Orthology more info
located_in sperm fibrous sheath	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: A-kinase anchor protein 14

Names: A kinase (PRKA) anchor protein 14; AKAP-14; TAKAP-1.2; Testis-specific A-kinase-anchoring-protein; testis-specific A-kinase-anchoring protein TAKAP-80

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.