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    notchl notch receptor, like [ Danio rerio (zebrafish) ]

    Gene ID: 569522, updated on 17-Aug-2024

    Summary

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    Official Symbol
    notchlprovided by ZNC
    Official Full Name
    notch receptor, likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070220-2
    See related
    Ensembl:ENSDARG00000088308 AllianceGenome:ZFIN:ZDB-GENE-070220-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to act upstream of or within Notch signaling pathway and cell differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See notchl in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (48645211..48673950, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (48703191..48731920, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC558761 Neighboring gene pre-B-cell leukemia homeobox 2 Neighboring gene transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Neighboring gene bromodomain containing 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of zebrafish (Danio rerio) cyclin-dependent kinase 5. Kanungo J, et al. Neurosci Lett, 2007 Feb 2. PMID 17178437, Free PMC Article
    2. Single-cell transcriptomic analysis of vascular endothelial cells in zebrafish embryos. Gurung S, et al. Sci Rep, 2022 Jul 29. PMID 35906287, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    neurogenic locus notch homolog protein 1
    Names
    notch homolog, like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      48645211..48673950 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002665009.6 → XP_002665055.3  neurogenic locus notch homolog protein 1

      UniProtKB/TrEMBL
      A0A8M1RHS0, X1WEZ2
      Related
      ENSDARP00000128794.1, ENSDART00000156969.2
      Conserved Domains (5) summary
      cd00204
      Location:436 → 556
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00066
      Location:73 → 101
      Notch; LNR domain
      pfam07684
      Location:179 → 239
      NODP; NOTCH protein
      pfam12796
      Location:441 → 533
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:436 → 467
      ANK; ANK repeat [structural motif]

    RNA

    1. XR_658599.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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