U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    FLOT1 flotillin 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 532573, updated on 10-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FLOT1provided by VGNC
    Official Full Name
    flotillin 1provided by VGNC
    Primary source
    VGNC:VGNC:29036
    See related
    BGD:BT10083; Ensembl:ENSBTAG00000009960
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FLOT1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (28286486..28296572)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132343632 Neighboring gene immediate early response 3 Neighboring gene tubulin beta class I Neighboring gene mediator of DNA damage checkpoint 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC143379

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of cell junction assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell-cell adhesion mediated by cadherin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein kinase C signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of receptor internalization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    flotillin-1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076887.1 → NP_001070355.1  flotillin-1

      See identical proteins and their annotated locations for NP_001070355.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123642
      UniProtKB/Swiss-Prot
      Q08DN8
      UniProtKB/TrEMBL
      Q3MHZ0
      Related
      ENSBTAP00000013135.5, ENSBTAT00000013135.6
      Conserved Domains (2) summary
      COG2268
      Location:4 → 419
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:30 → 175
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      28286486..28296572
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005223662.5 → XP_005223719.1  flotillin-1 isoform X1

      See identical proteins and their annotated locations for XP_005223719.1

      UniProtKB/Swiss-Prot
      Q08DN8
      UniProtKB/TrEMBL
      Q3MHZ0
      Conserved Domains (2) summary
      COG2268
      Location:4 → 419
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:30 → 175
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    2. XM_059880380.1 → XP_059736363.1  flotillin-1 isoform X1

      UniProtKB/Swiss-Prot
      Q08DN8

    3. XM_005223663.5 → XP_005223720.1  flotillin-1 isoform X1

      See identical proteins and their annotated locations for XP_005223720.1

      UniProtKB/Swiss-Prot
      Q08DN8
      UniProtKB/TrEMBL
      Q3MHZ0
      Conserved Domains (2) summary
      COG2268
      Location:4 → 419
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:30 → 175
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    4. XM_005223664.5 → XP_005223721.1  flotillin-1 isoform X1

      See identical proteins and their annotated locations for XP_005223721.1

      UniProtKB/Swiss-Prot
      Q08DN8
      UniProtKB/TrEMBL
      Q3MHZ0
      Conserved Domains (2) summary
      COG2268
      Location:4 → 419
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:30 → 175
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08DN8.1 GenPept UniProtKB/Swiss-Prot:Q08DN8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.