INSIG1 insulin induced gene 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: INSIG1provided by VGNC
Official Full Name: insulin induced gene 1provided by VGNC
Primary source: VGNC:VGNC:30217
See related: BGD:BT10003; Ensembl:ENSBTAG00000001592
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	4	NC_037331.1 (117125850..117138562)

Chromosome 4 - NC_037331.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

In Nanyang Chinese cattle, seven common haplotypes were identified in the INSIG1 gene based on four coding region SNPs.
Title: Haplotype combination of the bovine INSIG1 gene sequence variants and association with growth traits in Nanyang cattle.

Submit: New GeneRIF Correction

General gene information

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Markers

MARC_78971-78972:1245253242:1 (e-PCR)
- UniSTS:528139

MARC_78973-78974:1245271570:3 (e-PCR)
- UniSTS:528140

MARC_78975-78976:1245426971:1 (e-PCR)
- UniSTS:528141

MARC_78977-78978:1245427585:1 (e-PCR)
- UniSTS:528142

MARC_78981-78982:1245436959:1 (e-PCR)
- UniSTS:528143

MARC_78983-78984:1245439394:1 (e-PCR)
- UniSTS:528144

MARC_78987-78988:1245440230:2 (e-PCR)
- UniSTS:528145

Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in SREBP signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in SREBP-SCAP complex retention in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to insulin stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cholesterol biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of SREBP-SCAP-Insig complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: insulin-induced gene 1 protein

Names: INSIG-1; insulin induced protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.