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    ABCG8 ATP binding cassette subfamily G member 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 508829, updated on 4-Oct-2024

    Summary

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    Official Symbol
    ABCG8provided by VGNC
    Official Full Name
    ATP binding cassette subfamily G member 8provided by VGNC
    Primary source
    VGNC:VGNC:25486
    See related
    BGD:BT12056; Ensembl:ENSBTAG00000016366
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ABCG8 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (26079209..26097490)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene dynein cytoplasmic 2 light intermediate chain 1 Neighboring gene ATP binding cassette subfamily G member 5 Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene leucine rich pentatricopeptide repeat containing Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification, sequence analysis and mRNA tissue distribution of the bovine sterol transporters ABCG5 and ABCG8. Viturro E, et al. J Dairy Sci, 2006 Feb. PMID 16428624
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-binding cassette sub-family G member 8
    Names
    ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024663.1 → NP_001019834.1  ATP-binding cassette sub-family G member 8

      See identical proteins and their annotated locations for NP_001019834.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ001134
      UniProtKB/TrEMBL
      Q4ZJV8
      Conserved Domains (3) summary
      cd03234
      Location:60 → 293
      ABCG_White; White pigment protein homolog of ABCG transporter subfamily
      TIGR00955
      Location:46 → 659
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:398 → 602
      ABC2_membrane; ABC-2 type transporter

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      26079209..26097490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005212594.5 → XP_005212651.1  ATP-binding cassette sub-family G member 8 isoform X1

      UniProtKB/TrEMBL
      F1N3K2
      Related
      ENSBTAP00000021770.7, ENSBTAT00000021770.7
      Conserved Domains (3) summary
      cd03234
      Location:135 → 368
      ABCG_White; White pigment protein homolog of ABCG transporter subfamily
      TIGR00955
      Location:121 → 734
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:473 → 677
      ABC2_membrane; ABC-2 type transporter
    Nucleotide Protein Strain
    Heading Accession and Version

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