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    Mrps7 mitchondrial ribosomal protein S7 [ Mus musculus (house mouse) ]

    Gene ID: 50529, updated on 2-Nov-2024

    Summary

    Official Symbol
    Mrps7provided by MGI
    Official Full Name
    mitchondrial ribosomal protein S7provided by MGI
    Primary source
    MGI:MGI:1354367
    See related
    Ensembl:ENSMUSG00000046756 AllianceGenome:MGI:1354367
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S7mt; Rpms7; MRP-S7
    Summary
    Predicted to enable mRNA binding activity and rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation and ribosomal small subunit assembly. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 34. Orthologous to human MRPS7 (mitochondrial ribosomal protein S7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 28.7), kidney adult (RPKM 24.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mrps7 in Genome Data Viewer
    Location:
    11 E2; 11 80.9 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115494966..115498862)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115604140..115608036)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene nucleoporin 85 Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 3 Neighboring gene STARR-seq mESC enhancer starr_31165 Neighboring gene predicted gene, 25364 Neighboring gene STARR-positive B cell enhancer ABC_E7096 Neighboring gene MIF4G domain containing Neighboring gene solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 Neighboring gene STARR-seq mESC enhancer starr_31166 Neighboring gene STARR-positive B cell enhancer mm9_chr11:115494169-115494470 Neighboring gene STARR-positive B cell enhancer ABC_E8470 Neighboring gene STARR-positive B cell enhancer ABC_E2375 Neighboring gene growth factor receptor bound protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E10730 Neighboring gene STARR-positive B cell enhancer ABC_E7098

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within translation ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial small ribosomal subunit ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    part_of mitochondrial small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of mitochondrial small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein uS7m
    Names
    28S ribosomal protein S7, mitochondrial
    ribosomal protein, mitochondrial, S7
    NP_079581.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025305.3NP_079581.1  small ribosomal subunit protein uS7m precursor

      See identical proteins and their annotated locations for NP_079581.1

      Status: VALIDATED

      Source sequence(s)
      AK131937, AK162024
      Consensus CDS
      CCDS25642.1
      UniProtKB/Swiss-Prot
      Q3TSI9, Q80X85, Q9CV71
      Related
      ENSMUSP00000053033.9, ENSMUST00000058109.9
      Conserved Domains (1) summary
      cd14870
      Location:35240
      uS7_Mitochondria_Mammalian; Mammalian Mitochondrial homolog of Ribosomal Protein S7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      115494966..115498862
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)