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    Stra8 stimulated by retinoic acid 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500079, updated on 17-Aug-2024

    Summary

    Official Symbol
    Stra8provided by RGD
    Official Full Name
    stimulated by retinoic acid 8provided by RGD
    Primary source
    RGD:1562852
    See related
    EnsemblRapid:ENSRNOG00000010573 AllianceGenome:RGD:1562852
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562852
    Summary
    Predicted to enable protein dimerization activity. Predicted to be involved in several processes, including activation of meiosis; cellular response to retinoic acid; and germ cell development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human STRA8 (stimulated by retinoic acid 8). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 11.9) and Thymus (RPKM 7.6) See more
    Orthologs
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    Genomic context

    See Stra8 in Genome Data Viewer
    Location:
    4q22
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (64568580..64591914)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (63601443..63624777)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (62447724..62474802)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 140 Neighboring gene cell cycle regulator of NHEJ Neighboring gene WD repeat domain 91 Neighboring gene uncharacterized LOC103692099 Neighboring gene solute carrier family 23 member 4 Neighboring gene CCR4-NOT transcription complex, subunit 4 Neighboring gene uncharacterized LOC102553126

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in activation of meiosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in activation of meiosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to retinoic acid ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in male germ-line stem cell asymmetric division ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in meiotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in oogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in oogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in male germ cell nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    stimulated by retinoic acid 8; stimulated by retinoic acid gene 8 protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431814.1NP_001418743.1  stimulated by retinoic acid 8

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      64568580..64591914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236282.5XP_006236344.1  stimulated by retinoic acid gene 8 protein homolog

      UniProtKB/TrEMBL
      A6IEN5, D4ADQ4
      Related
      ENSRNOP00000014093.6, ENSRNOT00000014093.7