U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Lrrc34 leucine rich repeat containing 34 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499589, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Lrrc34provided by RGD
    Official Full Name
    leucine rich repeat containing 34provided by RGD
    Primary source
    RGD:1565052
    See related
    EnsemblRapid:ENSRNOG00000027935 AllianceGenome:RGD:1565052
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565052
    Summary
    Predicted to be involved in cell differentiation. Predicted to be located in cytoplasm and nucleolus. Orthologous to human LRRC34 (leucine rich repeat containing 34). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 105.1), Lung (RPKM 48.3) and 9 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Lrrc34 in Genome Data Viewer
    Location:
    2q24
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (114680787..114702961)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (112752294..112774463)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (116370013..116391964)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E, pseudogene 6 Neighboring gene heat shock protein family A (Hsp70) member 8, pseudogene 28 Neighboring gene leucine rich repeat containing 31 Neighboring gene leucine-rich repeats and IQ motif containing 4 Neighboring gene myoneurin Neighboring gene transfer RNA valine (anticodon AAC) 1 Neighboring gene actin-related protein T3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites. Hoffert JD, et al. Proc Natl Acad Sci U S A, 2006 May 2. PMID 16641100, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC114480

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    leucine-rich repeat-containing protein 34

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044696.1 → NP_001038161.1  leucine-rich repeat-containing protein 34

      See identical proteins and their annotated locations for NP_001038161.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097432
      UniProtKB/Swiss-Prot
      Q4V8D9
      Related
      ENSRNOP00000033262.5, ENSRNOT00000031730.7
      Conserved Domains (3) summary
      cd00116
      Location:98 → 347
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:79 → 103
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:245 → 314
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      114680787..114702961
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282360.1 → XP_063138430.1  leucine-rich repeat-containing protein 34 isoform X1

      UniProtKB/TrEMBL
      A6IHL8, G3V919

    2. XM_017591030.3 → XP_017446519.1  leucine-rich repeat-containing protein 34 isoform X1

      UniProtKB/TrEMBL
      A6IHL8, G3V919
      Related
      ENSRNOP00000109342.1, ENSRNOT00000152786.1
      Conserved Domains (2) summary
      sd00033
      Location:79 → 103
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:70 → 347
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    3. XM_039102871.2 → XP_038958799.1  leucine-rich repeat-containing protein 34 isoform X1

      UniProtKB/TrEMBL
      A6IHL8, G3V919
      Conserved Domains (2) summary
      sd00033
      Location:79 → 103
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:70 → 347
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    4. XM_017591031.3 → XP_017446520.1  leucine-rich repeat-containing protein 34 isoform X1

      UniProtKB/TrEMBL
      A6IHL8, G3V919
      Conserved Domains (2) summary
      sd00033
      Location:79 → 103
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:70 → 347
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    5. XM_039102872.1 → XP_038958800.1  leucine-rich repeat-containing protein 34 isoform X2

      Conserved Domains (2) summary
      sd00033
      Location:23 → 50
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:3 → 238
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V8D9.1 GenPept UniProtKB/Swiss-Prot:Q4V8D9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools