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    IFNB1 interferon beta 1 [ Felis catus (domestic cat) ]

    Gene ID: 493849, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IFNB1
    Official Full Name
    interferon beta 1
    Primary source
    VGNC:VGNC:67702
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Also known as
    IFNB
    Orthologs
    human mouse all
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    Genomic context

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    See IFNB1 in Genome Data Viewer
    Location:
    chromosome: D4
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D4 NC_058380.1 (45647408..45647968, complement)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D4 NC_018735.3 (47624644..47625204, complement)

    Chromosome D4 - NC_058380.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123381733 Neighboring gene interferon alpha-2-like Neighboring gene interferon alpha-2-like Neighboring gene interferon omega-1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assessment of the IFN-β response to four feline caliciviruses: Infection in CRFK cells. Tian J, et al. Infect Genet Evol, 2015 Aug. PMID 26051884
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables type I interferon receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in B cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in B cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in T cell activation involved in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in humoral immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in natural killer cell activation involved in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of peptidyl-serine phosphorylation of STAT protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to exogenous dsRNA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon beta
    Names
    IFN-beta
    interferon, beta 1, fibroblast

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009297.1 → NP_001009297.1  interferon beta precursor

      See identical proteins and their annotated locations for NP_001009297.1

      Status: PROVISIONAL

      Source sequence(s)
      AB021707
      UniProtKB/Swiss-Prot
      Q9N2J0
      UniProtKB/TrEMBL
      A1YQW1
      Conserved Domains (1) summary
      pfam00143
      Location:32 → 177
      Interferon; Interferon alpha/beta domain

    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058380.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      45647408..45647968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N2J0.1 GenPept UniProtKB/Swiss-Prot:Q9N2J0

    Gene LinkOut

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