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    LGR4 leucine rich repeat containing G protein-coupled receptor 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 476896, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LGR4provided by VGNC
    Official Full Name
    leucine rich repeat containing G protein-coupled receptor 4provided by VGNC
    Primary source
    VGNC:VGNC:42655
    See related
    Ensembl:ENSCAFG00845017676
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LGR4 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (49092130..49194350, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (47448894..47548000, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (48839453..48939290, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (48077244..48176850, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (48247673..48347510, complement)

    Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091587 Neighboring gene uncharacterized LOC106560206 Neighboring gene uncharacterized LOC119864901 Neighboring gene lin-7 homolog C, crumbs cell polarity complex component

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-hormone receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat-containing G-protein coupled receptor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051825.1 Reference ROS_Cfam_1.0

      Range
      49092130..49194350 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038430726.1 → XP_038286654.1  leucine-rich repeat-containing G-protein coupled receptor 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PKD6
      Related
      ENSCAFP00845024494.1, ENSCAFT00845031291.1
      Conserved Domains (4) summary
      sd00033
      Location:18 → 41
      LRR_RI; leucine-rich repeat [structural motif]
      cd15361
      Location:474 → 747
      7tmA_LGR4; leucine-rich repeats-containing G protein-coupled receptor 4, member of the class A family of seven-transmembrane G protein-coupled receptors
      NF033189
      Location:40 → 398
      internalin_A; class 1 internalin InlA
      pfam13855
      Location:2 → 52
      LRR_8; Leucine rich repeat

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049281.1 Alternate UMICH_Zoey_3.1

      Range
      48077244..48176850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038506051.1 → XP_038361979.1  leucine-rich repeat-containing G-protein coupled receptor 4 isoform X2

      Conserved Domains (3) summary
      PLN00113
      Location:34 → 445
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:59 → 82
      LRR_RI; leucine-rich repeat [structural motif]
      cd15361
      Location:539 → 812
      7tmA_LGR4; leucine-rich repeats-containing G protein-coupled receptor 4, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

      Range
      48247673..48347510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038633476.1 → XP_038489404.1  leucine-rich repeat-containing G-protein coupled receptor 4 isoform X3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

      Range
      48839453..48939290 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038569287.1 → XP_038425215.1  leucine-rich repeat-containing G-protein coupled receptor 4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0Q6X4, A0A8C0QD14, A0A8P0SF16
      Conserved Domains (3) summary
      PLN00113
      Location:34 → 445
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:59 → 82
      LRR_RI; leucine-rich repeat [structural motif]
      cd15361
      Location:539 → 812
      7tmA_LGR4; leucine-rich repeats-containing G protein-coupled receptor 4, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      47448894..47548000 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038456513.1 → XP_038312441.1  leucine-rich repeat-containing G-protein coupled receptor 4 isoform X5

      UniProtKB/TrEMBL
      A0A8C0Q6X4, A0A8C0QD14, A0A8P0SF16
      Conserved Domains (3) summary
      PLN00113
      Location:34 → 445
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:59 → 82
      LRR_RI; leucine-rich repeat [structural motif]
      cd15361
      Location:539 → 812
      7tmA_LGR4; leucine-rich repeats-containing G protein-coupled receptor 4, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version

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