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    CCL24 C-C motif chemokine ligand 24 [ Canis lupus familiaris (dog) ]

    Gene ID: 445452, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CCL24provided by VGNC
    Official Full Name
    C-C motif chemokine ligand 24provided by VGNC
    Primary source
    VGNC:VGNC:38886
    See related
    Ensembl:ENSCAFG00845004068
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See CCL24 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (6986790..7000238, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (8864028..8865941, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (7084112..7086021, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (6957433..6959341, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (6920823..6922728, complement)

    Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene huntingtin interacting protein 1 Neighboring gene carbonyl reductase [NADPH] 3-like Neighboring gene C-C motif chemokine ligand 26 Neighboring gene rhomboid domain containing 2 Neighboring gene cytochrome p450 oxidoreductase Neighboring gene transmembrane protein 120A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables CCR chemokine receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chemokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to interleukin-1 IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to tumor necrosis factor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to type II interferon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lymphocyte chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monocyte chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neutrophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C-C motif chemokine 24
    Names
    eosinophil chemotactic protein-2
    eotaxin-2
    small chemokine ligand 24
    small-inducible cytokine A24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003967.1 → NP_001003967.1  C-C motif chemokine 24 precursor

      See identical proteins and their annotated locations for NP_001003967.1

      Status: PROVISIONAL

      Source sequence(s)
      AB162851
      UniProtKB/Swiss-Prot
      Q68Y86
      UniProtKB/TrEMBL
      A0A8C0KJ40
      Conserved Domains (1) summary
      pfam00048
      Location:31 → 87
      IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051810.1 Reference ROS_Cfam_1.0

      Range
      6986790..7000238 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038667570.1 → XP_038523498.1  C-C motif chemokine 24 isoform X1

      UniProtKB/TrEMBL
      A0A8C0SGE2, A0A8I3RTB0
      Related
      ENSCAFP00845005810.1, ENSCAFT00845007319.1
      Conserved Domains (1) summary
      smart00199
      Location:110 → 169
      SCY; Intercrine alpha family (small cytokine C-X-C) (chemokine CXC)

    2. XM_038667571.1 → XP_038523499.1  C-C motif chemokine 24 isoform X2

      Conserved Domains (1) summary
      smart00199
      Location:110 → 169
      SCY; Intercrine alpha family (small cytokine C-X-C) (chemokine CXC)

    3. XM_038667572.1 → XP_038523500.1  C-C motif chemokine 24 isoform X3

      Conserved Domains (1) summary
      smart00199
      Location:58 → 117
      SCY; Intercrine alpha family (small cytokine C-X-C) (chemokine CXC)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049266.1 Alternate UMICH_Zoey_3.1

      Range
      6957433..6959341 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

      Range
      6920823..6922728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

      Range
      7084112..7086021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      8864028..8865941 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q68Y86.1 GenPept UniProtKB/Swiss-Prot:Q68Y86

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials