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    ZC3H11C zinc finger CCCH-type containing 11C [ Homo sapiens (human) ]

    Gene ID: 441155, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ZC3H11Cprovided by HGNC
    Official Full Name
    zinc finger CCCH-type containing 11Cprovided by HGNC
    Primary source
    HGNC:HGNC:56304
    See related
    Ensembl:ENSG00000214558 AllianceGenome:HGNC:56304
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis (RPKM 13.2), skin (RPKM 9.9) and 25 other tissues See more
    Orthologs
    all
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    Genomic context

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    See ZC3H11C in Genome Data Viewer
    Location:
    6q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (65301476..65306574)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (66455264..66460362)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (66011369..66016467)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene eyes shut homolog Neighboring gene uncharacterized LOC105377837 Neighboring gene NANOG hESC enhancer GRCh37_chr6:65716434-65717013 Neighboring gene uncharacterized LOC107986607 Neighboring gene uncharacterized LOC124901559 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92568 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92593 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92629 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92636 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92651 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92656 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92672 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92766 Neighboring gene Neanderthal introgressed variant-containing enhancers experimental_92772 and experimental_92778 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92831 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92928 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_92954 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:66278733-66279372 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_93128 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_93152 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_93271 Neighboring gene H3K4me1 hESC enhancers GRCh37_chr6:66348122-66348622 and GRCh37_chr6:66348623-66349123 Neighboring gene Neanderthal introgressed variant-containing enhancers experimental_93370 and experimental_93383 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_93446 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_93466 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_93494 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_93502 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_93582 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:66481227-66481728 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:66481729-66482228 Neighboring gene SLC25A51 pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. A proximity-dependent biotinylation map of a human cell. Go CD, et al. Nature, 2021 Jul. PMID 34079125
    2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger CCCH domain-containing protein 11C
    Names
    zinc finger CCCH-type containing 11A-like
    zinc finger CCCH-type domain-containing-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271675.2 → NP_001258604.1  zinc finger CCCH domain-containing protein 11C

      See identical proteins and their annotated locations for NP_001258604.1

      Status: VALIDATED

      Source sequence(s)
      AL365217
      Consensus CDS
      CCDS93939.1
      UniProtKB/Swiss-Prot
      P0DQW0
      UniProtKB/TrEMBL
      A0A8V8TLD8, B4DYM8
      Related
      ENSP00000513306.1, ENST00000398578.3
      Conserved Domains (2) summary
      smart00356
      Location:6 → 28
      ZnF_C3H1; zinc finger
      pfam15663
      Location:2 → 110
      zf-CCCH_3; Zinc-finger containing family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      65301476..65306574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017010889.3 → XP_016866378.1  zinc finger CCCH domain-containing protein 11C isoform X1

      UniProtKB/Swiss-Prot
      P0DQW0
      UniProtKB/TrEMBL
      A0A8V8TLD8, B4DYM8
      Conserved Domains (2) summary
      smart00356
      Location:6 → 28
      ZnF_C3H1; zinc finger
      pfam15663
      Location:2 → 110
      zf-CCCH_3; Zinc-finger containing family

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      66455264..66460362
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054355511.1 → XP_054211486.1  zinc finger CCCH domain-containing protein 11C isoform X1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_006000.3: Suppressed sequence

      Description
      NG_006000.3: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0DQW0.1 GenPept UniProtKB/Swiss-Prot:P0DQW0

    Gene LinkOut

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