U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    HSP90AA1 heat shock protein 90 alpha family class A member 1 [ Gallus gallus (chicken) ]

    Gene ID: 423463, updated on 10-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    HSP90AA1provided by CGNC
    Official Full Name
    heat shock protein 90 alpha family class A member 1provided by CGNC
    Primary source
    CGNC:51974
    See related
    Ensembl:ENSGALG00010016869
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    HSP90
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See HSP90AA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (48992977..49000184, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (48971047..48978293, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2 regulatory subunit B'gamma Neighboring gene dynein cytoplasmic 1 heavy chain 1 Neighboring gene uncharacterized LOC121113247 Neighboring gene WD repeat domain 20 Neighboring gene MOK protein kinase Neighboring gene transfer RNA isoleucine (anticodon AAU)

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Isolation and functional analysis of chicken 90-kDa heat shock protein gene promoter. Vourc'h C, et al. Nucleic Acids Res, 1989 Jul 11. PMID 2762125, Free PMC Article
    2. The cDNA-derived amino acid sequence of chick heat shock protein Mr 90,000 (HSP 90) reveals a "DNA like" structure: potential site of interaction with steroid receptors. Binart N, et al. Biochem Biophys Res Commun, 1989 Feb 28. PMID 2923621
    3. Expression of heat shock protein 90 (Hsp90) and transcription of its corresponding mRNA in broilers exposed to high temperature. Lei L, et al. Br Poult Sci, 2009 Jul. PMID 19735020
    4. Chicken heat shock protein 90 is a component of the putative cellular receptor complex of infectious bursal disease virus. Lin TW, et al. J Virol, 2007 Aug. PMID 17522206, Free PMC Article
    5. Genetic polymorphisms in part of intron 7 and exon 8 of HSP90AA1 gene and its association with heat tolerance traits in two exotic layer chicken strains. Irivboje YI, et al. Trop Anim Health Prod, 2020 May. PMID 31707685

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Genetic polymorphisms in part of intron 7 and exon 8 of HSP90AA1 gene and its association with heat tolerance traits in two exotic layer chicken strains.
      Title: Genetic polymorphisms in part of intron 7 and exon 8 of HSP90AA1 gene and its association with heat tolerance traits in two exotic layer chicken strains.
    2. Hsp90alpha but not Hsp90beta binds with the CpG oligodeoxynucleotides (ODN 2007) and may play a major role in CpG ODN(2007) induced immunoactivation in avian macrophage cells.
      Title: Role of Hsp90 in CpG ODN mediated immunostimulation in avian macrophages.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables disordered domain specific binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to heat IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein stabilization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in myelin sheath IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    heat shock protein HSP 90-alpha
    Names
    heat shock 90 kDa protein
    heat shock protein 90kDa alpha (cytosolic), class A member 1
    heat shock protein HSP90 alpha
    NP_001103255.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109785.2 → NP_001103255.2  heat shock protein HSP 90-alpha

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      A0A1D5PUL6
      Related
      ENSGALP00010023655.1, ENSGALT00010040690.1
      Conserved Domains (1) summary
      PTZ00272
      Location:17 → 728
      PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      48992977..49000184 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      48971047..48978293 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P11501.3 GenPept UniProtKB/Swiss-Prot:P11501

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.