Ggt6 gamma-glutamyl transferase 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Ggt6provided by RGD
Full Name: gamma-glutamyl transferase 6provided by RGD
Primary source: RGD:1303335
See related: EnsemblRapid:ENSRNOG00000015210 AllianceGenome:RGD:1303335
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable glutathione hydrolase activity; hypoglycin A gamma-glutamyl transpeptidase activity; and leukotriene C4 gamma-glutamyl transferase activity. Predicted to be involved in glutathione biosynthetic process and proteolysis. Predicted to be integral component of membrane. Orthologous to human GGT6 (gamma-glutamyltransferase 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 5.4), Kidney (RPKM 4.9) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q24

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (57550447..57553461)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (57051977..57054900)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (58995253..58998431)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables glutathione hydrolase activity	IEA Inferred from Electronic Annotation more info
enables leukotriene C4 gamma-glutamyl transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glutathione biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glutathione hydrolase 6

Names: GGT 6; gamma-glutamyltransferase 6; gamma-glutamyltranspeptidase 6

NP_001002820.1

EC 2.3.2.2

EC 3.4.19.13

XP_063125639.1

EC 2.3.2.2

EC 3.4.19.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.