HBB hemoglobin, beta [Sus scrofa (pig)] - Gene

Summary

Gene symbol: HBB
Gene description: hemoglobin, beta
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Broad expression in spleen (RPKM 5179.3), lung (RPKM 2205.3) and 7 other tissues See more
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Genomic context

Location:: chromosome: 9

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	9	NC_010451.4 (4800683..4801941, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	9	NC_010451.3 (5633105..5634363, complement)

Chromosome 9 - NC_010451.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

In this study, hemoglobin subunit beta was identified as a classical swine fever virus capsid protein-binding protein by glutathione S-transferase pulldown and subsequent mass spectrometry analysis of PK-15 cells.
Title: Hemoglobin subunit beta interacts with the capsid protein and antagonizes the growth of classical swine fever virus.

Submit: New GeneRIF Correction

General gene information

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Markers

G47279 (e-PCR)
- UniSTS:108062

Hbb-b1 (e-PCR), detects polymorphism
- UniSTS:516684

PMC21968P1 (e-PCR)
- UniSTS:272086

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables haptoglobin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables hemoglobin alpha binding	IEA Inferred from Electronic Annotation more info	PubMed
enables organic acid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables oxygen binding	IEA Inferred from Electronic Annotation more info	PubMed
enables oxygen carrier activity	IEA Inferred from Electronic Annotation more info	PubMed
enables peroxidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in hydrogen peroxide catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in oxygen transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in blood microparticle	IEA Inferred from Electronic Annotation more info	PubMed
part_of haptoglobin-hemoglobin complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of hemoglobin complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: hemoglobin subunit beta

Names: Beta-globin; Hemoglobin beta chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001144841.1 → NP_001138313.1 hemoglobin subunit beta

See identical proteins and their annotated locations for NP_001138313.1

Status: PROVISIONAL

Source sequence(s)

X86791

UniProtKB/Swiss-Prot

P02067, Q29025

UniProtKB/TrEMBL

A0A8D1E0S1

Conserved Domains (1) summary

cd08925
Location:7 → 146

Hb-beta_like; Hemoglobin beta, gamma, delta, epsilon, and related Hb subunits