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    Mrjp1 major royal jelly protein 1 [ Apis mellifera (honey bee) ]

    Gene ID: 406090, updated on 9-Nov-2023

    Summary

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    Gene symbol
    Mrjp1
    Gene description
    major royal jelly protein 1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Apis mellifera
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Anthophila; Apidae; Apis
    Also known as
    GB14888; GB55205; p56kP-4
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    Genomic context

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    See Mrjp1 in Genome Data Viewer
    Location:
    chromosome: LG11
    Exon count:
    7
    Annotation release Status Assembly LG Location
    104 current Amel_HAv3.1 (GCF_003254395.2) LG11 NC_037648.1 (2274667..2277905)
    103 previous assembly Amel_4.5 (GCF_000002195.4) LG11 NC_007080.3 (2569592..2572830)

    Linkage Group LG11 - NC_037648.1Genomic Context describing neighboring genes Neighboring gene yellow-e3 Neighboring gene major royal jelly protein 3 Neighboring gene major royal jelly protein 4 Neighboring gene major royal jelly protein 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantification of major royal jelly protein 1 in fresh royal jelly by indirect enzyme-linked immunosorbent assay. Yamaguchi K, et al. Biosci Biotechnol Biochem, 2013. PMID 23748766
    2. Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera). Fontana R, et al. Peptides, 2004 Jun. PMID 15203237
    3. A royal jelly protein is expressed in a subset of Kenyon cells in the mushroom bodies of the honey bee brain. Kucharski R, et al. Naturwissenschaften, 1998 Jul. PMID 9722965
    4. How Honeybees Defy Gravity with Royal Jelly to Raise Queens. Buttstedt A, et al. Curr Biol, 2018 Apr 2. PMID 29551410
    5. Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools. Mandacaru SC, et al. Biochemistry, 2017 Mar 21. PMID 28252287, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Most abundant protein in the hypopharyngeal gland and fifth most abundant protein in the brain of 8-days old nurse honey bees(based on quantitative mass spectrometry).
      Title: The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life.
    2. Polymerizes in complex with apisimin (Gene ID: 406093) at acidic pH into long fibrous structures that build the basis for the high viscosity of honey bee royal jelly to hold queen larvae on the royal jelly surface.
      Title: How Honeybees Defy Gravity with Royal Jelly to Raise Queens.
    3. Mass spectrometry data demonstrate that the native complexes of royal jelly predominantly exist in a four MRJP1 and four apisimin molecules stoichiometry.
      Title: Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools.
    4. These results suggest that MRJP1 exists mainly as apisin in royal jelly.
      Title: Quantification of major royal jelly protein 1 in fresh royal jelly by indirect enzyme-linked immunosorbent assay.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    major royal jelly protein 1
    Names
    56-kDa protein 4
    MRJP-1
    apalbumin 1
    apisin subunit MRJP1
    bee-milk protein
    milk protein
    royalactin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011579.1 → NP_001011579.1  major royal jelly protein 1 precursor

      See identical proteins and their annotated locations for NP_001011579.1

      Status: PROVISIONAL

      Source sequence(s)
      AF000633
      UniProtKB/Swiss-Prot
      C6K481, O18330, Q548D6
      Conserved Domains (1) summary
      pfam03022
      Location:122 → 416
      MRJP; Major royal jelly protein

    RefSeqs of Annotated Genomes: Apis mellifera Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Amel_HAv3.1 Primary Assembly

    Genomic

    1. NC_037648.1 Reference Amel_HAv3.1 Primary Assembly

      Range
      2274667..2277905
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O18330.1 GenPept UniProtKB/Swiss-Prot:O18330

    Gene LinkOut

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