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    DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit [ Canis lupus familiaris (dog) ]

    Gene ID: 404012, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DDOSTprovided by VGNC
    Official Full Name
    dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunitprovided by VGNC
    Primary source
    VGNC:VGNC:39841
    See related
    Ensembl:ENSCAFG00845002430
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    OST48
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See DDOST in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (78835418..78842667)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (74782846..74790095)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (77669554..77676814)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (75654130..75661378)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (76665950..76673196)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 5 Neighboring gene uncharacterized LOC111093710 Neighboring gene kinesin family member 17 Neighboring gene PTEN induced kinase 1 Neighboring gene uncharacterized LOC119870450 Neighboring gene cytidine deaminase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The 48-kDa subunit of the mammalian oligosaccharyltransferase complex is homologous to the essential yeast protein WBP1. Silberstein S, et al. J Biol Chem, 1992 Nov 25. PMID 1429707
    2. Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits. Shibatani T, et al. Biochemistry, 2005 Apr 26. PMID 15835887
    3. Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties. Kelleher DJ, et al. Mol Cell, 2003 Jul. PMID 12887896
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in protein N-linked glycosylation via asparagine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of oligosaccharyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
    Names
    DDOST 48 kDa subunit
    dolichyl-diphosphooligosaccharide-protein glycosyltransferase
    oligosaccharyl transferase 48 kDa subunit
    oligosaccharyltransferase 48 kDa subunit
    NP_001003321.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003321.1 → NP_001003321.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor

      See identical proteins and their annotated locations for NP_001003321.1

      Status: PROVISIONAL

      Source sequence(s)
      M98392
      UniProtKB/Swiss-Prot
      Q05052
      UniProtKB/TrEMBL
      A0A8P0NGG8
      Related
      ENSCAFP00845003507.1, ENSCAFT00845004387.1
      Conserved Domains (1) summary
      pfam03345
      Location:37 → 444
      DDOST_48kD; Oligosaccharyltransferase 48 kDa subunit beta

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      78835418..78842667
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      75654130..75661378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      76665950..76673196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      77669554..77676814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      74782846..74790095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05052.1 GenPept UniProtKB/Swiss-Prot:Q05052

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    Research Materials