EPCAM epithelial cell adhesion molecule [Sus scrofa (pig)] - Gene

Summary

Official Symbol: EPCAMprovided by VGNC
Official Full Name: epithelial cell adhesion moleculeprovided by VGNC
Primary source: VGNC:VGNC:87726
See related: Ensembl:ENSSSCG00000008429
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: EGP; Ep-CAM; TACSTD1
Expression: Biased expression in kidney (RPKM 131.9), lung (RPKM 69.2) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	3	NC_010445.4 (93169800..93185221, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	3	NC_010445.3 (99312713..99328225, complement)

Chromosome 3 - NC_010445.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Ep-CAM may act as a physical homophilic interaction molecule between IELs and IECs at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection [Ep-CAM]
Title: Biological role of Ep-CAM in the physical interaction between epithelial cells and lymphocytes in intestinal epithelium.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cadherin binding involved in cell-cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in bicellular tight junction	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: epithelial cell adhesion molecule

Names: epithelial glycoprotein; tumor-associated calcium signal transducer 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214419.1 → NP_999584.1 epithelial cell adhesion molecule precursor

See identical proteins and their annotated locations for NP_999584.1

Status: PROVISIONAL

Source sequence(s)

AB161197

UniProtKB/Swiss-Prot

Q75QW1

UniProtKB/TrEMBL

A0A1X9RRB4, A0A8D0P4L0

Related

ENSSSCP00000045246.1, ENSSSCT00000061463.2

Conserved Domains (1) summary

cd00191
Location:65 → 125

TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases