EPOR erythropoietin receptor [Sus scrofa (pig)] - Gene

Summary

Official Symbol: EPORprovided by VGNC
Official Full Name: erythropoietin receptorprovided by VGNC
Primary source: VGNC:VGNC:87746
See related: Ensembl:ENSSSCG00000013618
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Annotation information: Annotation category: partial on reference assembly
Expression: Biased expression in spleen (RPKM 4.3), ovary (RPKM 3.7) and 4 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	2	NC_010444.4 (70063601..70068821, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	2	NC_010444.3 (70426996..70432219, complement)

Chromosome 2 - NC_010444.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables erythropoietin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cytokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hemopoiesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: erythropoietin receptor

Names: EPO-R

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214292.1 → NP_999457.1 erythropoietin receptor precursor

See identical proteins and their annotated locations for NP_999457.1

Status: PROVISIONAL

Source sequence(s)

AF274305

UniProtKB/Swiss-Prot

Q9MYZ9

UniProtKB/TrEMBL

A0A8D0VXC2, B0ZYW8

Related

ENSSSCP00000014472.2, ENSSSCT00000014873.5

Conserved Domains (2) summary

cd00063
Location:147 → 245

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam09067
Location:37 → 141

EpoR_lig-bind; Erythropoietin receptor, ligand binding