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    PGD phosphogluconate dehydrogenase [ Sus scrofa (pig) ]

    Gene ID: 397546, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PGDprovided by VGNC
    Official Full Name
    phosphogluconate dehydrogenaseprovided by VGNC
    Primary source
    VGNC:VGNC:91348
    See related
    Ensembl:ENSSSCG00000003402
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in subcutaneous adipose (RPKM 74.6), lung (RPKM 74.2) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See PGD in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (70675751..70692697)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (64608578..64625512)

    Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene kinesin family member 1B Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene apoptosis-inducing, TAF9-like domain 1 Neighboring gene cortistatin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Isolation, characterization and chromosomal assignment of a partial cDNA for porcine 6-phosphogluconate dehydrogenase. Harbitz I, et al. Hereditas, 1990. PMID 2361879
    2. Localization of the PGD and TGF beta-1 loci to pig chromosome 6q. Yerle M, et al. Anim Genet, 1990. PMID 2090012
    3. Analysis of the gluconate (gnt) operon of Bacillus subtilis. Reizer A, et al. Mol Microbiol, 1991 May. PMID 1659648
    4. Linkage relationships between ALPL, ENO1, GPI, PGD, and TGFB1 on porcine chromosome 6. Clamp PA, et al. Genomics, 1993 Aug. PMID 8104872
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphogluconate dehydrogenase (decarboxylating) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-gluconate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pentose-phosphate shunt IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pentose-phosphate shunt, oxidative branch IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: 6-phosphogluconate dehydrogenase, decarboxylating
    Names
    6-phosphogluconate dehydrogenase, decarboxylating

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

      Range
      70675751..70692697
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003127557.4 → XP_003127605.2  LOW QUALITY PROTEIN: 6-phosphogluconate dehydrogenase, decarboxylating

      UniProtKB/TrEMBL
      A0A480YSA5, A0A4X1W9L5, A0A5G2QR34
      Related
      ENSSSCP00000003687.3, ENSSSCT00000003774.4
      Conserved Domains (1) summary
      PRK09287
      Location:14 → 470
      PRK09287; 6-phosphogluconate dehydrogenase; Validated
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P14332.3 GenPept UniProtKB/Swiss-Prot:P14332

    Gene LinkOut

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    Research Materials