U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    MYH2 myosin, heavy chain 2, skeletal muscle, adult [ Sus scrofa (pig) ]

    Gene ID: 397256, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    MYH2
    Gene description
    myosin, heavy chain 2, skeletal muscle, adult
    See related
    Ensembl:ENSSSCG00000029441
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Biased expression in psoas major muscle (RPKM 1702.2), longissimus dorsi muscle (RPKM 1223.1) and 1 other tissue See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MYH2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (55252974..55278820, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (58205953..58230234)

    Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene myosin, heavy chain 4, skeletal muscle Neighboring gene myosin, heavy chain 1, skeletal muscle, adult Neighboring gene myosin heavy chain 3 Neighboring gene synthesis of cytochrome C oxidase 1 Neighboring gene ADP-ribose/CDP-alcohol diphosphatase, manganese dependent

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Molecular characterization of a developmentally regulated porcine skeletal myosin heavy chain gene and its 5' regulatory region. Chang KC, et al. J Cell Sci, 1995 Apr. PMID 7615692
    2. Differences in molecular structure among the porcine myosin heavy chain-2a, -2x, and -2b isoforms. Chikuni K, et al. Meat Sci, 2001 Mar. PMID 22061506
    3. Porcine myosin-VI: characterization of a new mammalian unconventional myosin. Hasson T, et al. J Cell Biol, 1994 Oct. PMID 7929586, Free PMC Article
    4. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    5. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytoskeletal motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    myosin-2
    Names
    fast myosin heavy chain
    myHC-2a
    myosin heavy chain 2
    myosin heavy chain 2a
    myosin heavy chain, skeletal muscle, adult 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214136.1 → NP_999301.1  myosin-2

      See identical proteins and their annotated locations for NP_999301.1

      Status: PROVISIONAL

      Source sequence(s)
      AB025260
      UniProtKB/Swiss-Prot
      Q9TV63
      UniProtKB/TrEMBL
      A0A8D1T9C0, A0A8D1UCG7
      Related
      ENSSSCP00000019078.3, ENSSSCT00000019597.5
      Conserved Domains (6) summary
      cl22853
      Location:100 → 770
      Motor_domain; Myosin and Kinesin motor domain
      pfam00063
      Location:88 → 770
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:850 → 1927
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:36 → 73
      Myosin_N; Myosin N-terminal SH3-like domain
      cl19219
      Location:1670 → 1767
      DUF342; Protein of unknown function (DUF342)
      cl23720
      Location:965 → 1098
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

      Range
      55252974..55278820 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021066217.1 → XP_020921876.1  myosin-2 isoform X1

      UniProtKB/TrEMBL
      A0A4X1SL20, A0A8D1T9C0, A0A8D1UCG7
      Conserved Domains (3) summary
      pfam02736
      Location:35 → 73
      Myosin_N; Myosin N-terminal SH3-like domain
      cl22853
      Location:100 → 770
      Motor_domain; Myosin and Kinesin motor domain
      cl25732
      Location:850 → 1927
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_021066216.1 → XP_020921875.1  myosin-2 isoform X1

      UniProtKB/TrEMBL
      A0A4X1SL20, A0A8D1T9C0, A0A8D1UCG7
      Conserved Domains (3) summary
      pfam02736
      Location:35 → 73
      Myosin_N; Myosin N-terminal SH3-like domain
      cl22853
      Location:100 → 770
      Motor_domain; Myosin and Kinesin motor domain
      cl25732
      Location:850 → 1927
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9TV63.1 GenPept UniProtKB/Swiss-Prot:Q9TV63

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials