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    GDF11 growth differentiation factor 11 [ Sus scrofa (pig) ]

    Gene ID: 397254, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GDF11provided by VGNC
    Official Full Name
    growth differentiation factor 11provided by VGNC
    Primary source
    VGNC:VGNC:88398
    See related
    Ensembl:ENSSSCG00000000363
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    BMP11
    Expression
    Ubiquitous expression in spleen (RPKM 2.8), ovary (RPKM 2.8) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See GDF11 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (21191322..21199024)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (22671244..22678880)

    Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene basic proline-rich protein-like Neighboring gene uncharacterized LOC102162669 Neighboring gene CD63 molecule Neighboring gene SAP domain containing ribonucleoprotein Neighboring gene uncharacterized LOC110260684 Neighboring gene uncharacterized LOC106510299

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Radiation hybrid mapping of porcine bone morphogenetic protein 11 (BMP11) gene to pig chromosomes 5. Geng LY, et al. Anim Genet, 2005 Apr. PMID 15771745
    2. Induction of reparative dentin formation by ultrasound-mediated gene delivery of growth/differentiation factor 11. Nakashima M, et al. Hum Gene Ther, 2003 Apr 10. PMID 12718768
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    growth/differentiation factor 11
    Names
    bone morphogenetic protein 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001244310.1 → NP_001231239.1  growth/differentiation factor 11 precursor

      Status: PROVISIONAL

      Source sequence(s)
      AEMK02000033, AF339155, AY722391, DV936887, HQ657211
      UniProtKB/TrEMBL
      E7ECV9
      Related
      ENSSSCP00000000380.2, ENSSSCT00000000386.5
      Conserved Domains (2) summary
      smart00204
      Location:310 → 404
      TGFB; Transforming growth factor-beta (TGF-beta) family
      pfam00688
      Location:58 → 282
      TGFb_propeptide; TGF-beta propeptide

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

      Range
      21191322..21199024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021091131.1 → XP_020946790.1  growth/differentiation factor 11 isoform X1

      Conserved Domains (1) summary
      pfam00688
      Location:58 → 282
      TGFb_propeptide; TGF-beta propeptide
    Nucleotide Protein Strain
    Heading Accession and Version

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