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    GSTO1 glutathione S-transferase omega 1 [ Sus scrofa (pig) ]

    Gene ID: 397117, updated on 5-Mar-2024

    Summary

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    Gene symbol
    GSTO1
    Gene description
    glutathione S-transferase omega 1
    See related
    Ensembl:ENSSSCG00000022351
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    SPG-R; GSTO 1-1
    Expression
    Broad expression in liver (RPKM 459.1), mixtures (RPKM 194.9) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See GSTO1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (115206434..115216624)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (125175630..125185821)

    Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene SWI5 dependent homologous recombination repair protein 1 Neighboring gene cilia and flagella associated protein 43 Neighboring gene uncharacterized LOC100623931 Neighboring gene glutathione S-transferase omega 2 Neighboring gene inositol 1,4,5-trisphosphate receptor interacting protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Purification and characterization of a glutathione S-transferase Omega in pig: evidence for two distinct organ-specific transcripts. Rouimi P, et al. Biochem J, 2001 Aug 15. PMID 11485575, Free PMC Article
    2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutathione dehydrogenase (ascorbate) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-ascorbic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutathione S-transferase omega-1
    Names
    GSTO-1
    MMA(V) reductase
    S-(Phenacyl)glutathione reductase
    glutathione S-transferase omega 1-1
    glutathione-dependent dehydroascorbate reductase
    monomethylarsonic acid reductase
    NP_999215.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214050.2 → NP_999215.1  glutathione S-transferase omega-1

      See identical proteins and their annotated locations for NP_999215.1

      Status: PROVISIONAL

      Source sequence(s)
      AF188838
      UniProtKB/Swiss-Prot
      Q9N1F5
      UniProtKB/TrEMBL
      A0A481BZ29, A0A8D1QJJ7
      Related
      ENSSSCP00000011305.2, ENSSSCT00000011607.4
      Conserved Domains (3) summary
      cd03184
      Location:108 → 229
      GST_C_Omega; C-terminal, alpha helical domain of Class Omega Glutathione S-transferases
      COG0625
      Location:26 → 225
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03055
      Location:5 → 94
      GST_N_Omega; GST_N family, Class Omega subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

      Range
      115206434..115216624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N1F5.2 GenPept UniProtKB/Swiss-Prot:Q9N1F5

    Gene LinkOut

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