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    TFRC transferrin receptor [ Sus scrofa (pig) ]

    Gene ID: 397062, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TFRCprovided by VGNC
    Official Full Name
    transferrin receptorprovided by VGNC
    Primary source
    VGNC:VGNC:93925
    See related
    Ensembl:ENSSSCG00000011848
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    trfr
    Annotation information
    Annotation category: partial on reference assembly
    Expression
    Broad expression in heart (RPKM 57.9), psoas major muscle (RPKM 55.1) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See TFRC in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (133976765..133997554)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (143414634..143435426)

    Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 19 Neighboring gene uncharacterized LOC100512560 Neighboring gene DNA polymerase delta subunit 2 pseudogene Neighboring gene 60S ribosomal protein L17 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Characterization of polymorphisms of transferrin receptor and their association with susceptibility to ETEC F4ab/ac in pigs. Wang Y, et al. J Anim Breed Genet, 2007 Aug. PMID 17651325
    2. Inheritance of the F4ab, F4ac and F4ad E. coli receptors in swine and examination of four candidate genes for F4acR. Python P, et al. J Anim Breed Genet, 2005 Apr. PMID 16130451
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two polymorphisms are identified in a single exon aafter comparaative sequencing analysis.
      Title: Characterization of polymorphisms of transferrin receptor and their association with susceptibility to ETEC F4ab/ac in pigs.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transferrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transferrin transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transferrin receptor protein 1
    Names
    TR
    tfR
    tfR1
    transferrin receptor (p90, CD71)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214001.1 → NP_999166.1  transferrin receptor protein 1

      See identical proteins and their annotated locations for NP_999166.1

      Status: PROVISIONAL

      Source sequence(s)
      AF416763
      UniProtKB/Swiss-Prot
      Q8HZV3
      UniProtKB/TrEMBL
      A0A8D1APU0, D7RK08
      Related
      ENSSSCP00000029501.3, ENSSSCT00000034535.4
      Conserved Domains (3) summary
      cd02128
      Location:213 → 385
      PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
      pfam04253
      Location:650 → 758
      TFR_dimer; Transferrin receptor-like dimerization domain
      cl14876
      Location:393 → 618
      Zinc_peptidase_like; Zinc peptidases M18, M20, M28, and M42

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

      Range
      133976765..133997554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8HZV3.1 GenPept UniProtKB/Swiss-Prot:Q8HZV3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.