PSMB8 proteasome 20S subunit beta 8 [Sus scrofa (pig)] - Gene

Summary

Official Symbol: PSMB8provided by VGNC
Official Full Name: proteasome 20S subunit beta 8provided by VGNC
Primary source: VGNC:VGNC:91910
See related: Ensembl:ENSSSCG00000026951
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: LMP7
Expression: Broad expression in spleen (RPKM 194.3), lung (RPKM 107.7) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	7	NC_010449.5 (25058456..25061666, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	7	NC_010449.4 (29425070..29428073, complement)

Chromosome 7 - NC_010449.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results suggest LMP2/LMP7 gene should be regarded as molecular marker to estimate animal's immune status for their effects on hematological traits.
Title: Association analysis of polymorphisms of porcine LMP2 and LMP7 genes with haematological traits.

Submit: New GeneRIF Correction

General gene information

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Markers

MARC_5881-5882:997299388:1 (e-PCR)
- UniSTS:269597

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables threonine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis involved in protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of proteasome core complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: proteasome subunit beta type-8

Names: Macropain subunit C13; Multicatalytic endopeptidase complex subunit C13; Proteasome component C13; Proteasome subunit beta-5i; low molecular mass protein 7; proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7); proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7); proteasome beta 8 subunit; proteasome subunit LMP7; proteasome subunit beta 8

NP_999100.2

EC 3.4.25.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213935.2 → NP_999100.2 proteasome subunit beta type-8

Status: VALIDATED

Source sequence(s)

AEMK02000055, DB815752

UniProtKB/TrEMBL

A0A480YVH7, A0A4X1UYA4, A0A8D0M8J6, A5D9J4

Related

ENSSSCP00000001581.1, ENSSSCT00000001623.5

Conserved Domains (1) summary

cd03761
Location:73 → 260

proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...