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    VCL vinculin [ Sus scrofa (pig) ]

    Gene ID: 396974, updated on 17-Aug-2024

    Summary

    Official Symbol
    VCLprovided by VGNC
    Official Full Name
    vinculinprovided by VGNC
    Primary source
    VGNC:VGNC:94812
    See related
    Ensembl:ENSSSCG00000010313
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    VIN
    Expression
    Ubiquitous expression in lung (RPKM 64.5), heart (RPKM 47.6) and 8 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See VCL in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (76700143..76811875)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (82826487..82938103)

    Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene undifferentiated embryonic cell transcription factor 1-like Neighboring gene calcium/calmodulin dependent protein kinase II gamma Neighboring gene N-deacetylase and N-sulfotransferase 2 Neighboring gene atherin-like Neighboring gene plasminogen activator, urokinase Neighboring gene adaptor related protein complex 3 subunit mu 1 Neighboring gene adenosine kinase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    vinculin
    Names
    metavinculin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213934.1NP_999099.1  vinculin

      See identical proteins and their annotated locations for NP_999099.1

      Status: PROVISIONAL

      Source sequence(s)
      AF165172
      UniProtKB/TrEMBL
      A0A2C9F393, A0A4X1SRJ9
      Related
      ENSSSCP00000065820.1, ENSSSCT00000087228.1
      Conserved Domains (1) summary
      pfam01044
      Location:661067
      Vinculin; Vinculin family

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

      Range
      76700143..76811875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005671074.3XP_005671131.1  vinculin isoform X3

      UniProtKB/TrEMBL
      A0A2C9F393, A0A4X1SRF3, A0A4X1SRJ9
      Conserved Domains (1) summary
      pfam01044
      Location:661066
      Vinculin; Vinculin family
    2. XM_021072078.1XP_020927737.1  vinculin isoform X1

      UniProtKB/Swiss-Prot
      P26234, Q8WMK3
      UniProtKB/TrEMBL
      A0A2C9F393, A0A4X1SRJ9
      Related
      ENSSSCP00000010997.1, ENSSSCT00000011289.4
      Conserved Domains (1) summary
      pfam01044
      Location:661135
      Vinculin; Vinculin family
    3. XM_005671073.3XP_005671130.1  vinculin isoform X2

      UniProtKB/TrEMBL
      A0A2C9F393, A0A4X1SRJ9, A0A8D0PFK1
      Related
      ENSSSCP00000010998.2, ENSSSCT00000011290.4
      Conserved Domains (1) summary
      pfam01044
      Location:661134
      Vinculin; Vinculin family