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    CD3E CD3e molecule [ Gallus gallus (chicken) ]

    Gene ID: 396062, updated on 10-Oct-2024

    Summary

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    Symbol
    CD3Eprovided by CGNC
    Full Name
    CD3e moleculeprovided by CGNC
    Primary source
    CGNC:5597
    See related
    Ensembl:ENSGALG00010023715
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CD3E in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 24 NC_052555.1 (5503915..5511817)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 24 NC_052596.1 (5464206..5472104)

    Chromosome 24 - NC_052555.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101747663 Neighboring gene junction adhesion molecule like Neighboring gene myelin protein zero like 3 Neighboring gene myelin protein zero like 2 Neighboring gene CD3d molecule Neighboring gene zw10 kinetochore protein Neighboring gene transmembrane protease, serine 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and analysis of the chicken CD3epsilon gene. Göbel TW, et al. Eur J Immunol, 1997 Jan. PMID 9022018
    2. Structure of the chicken CD3εδ/γ heterodimer and its assembly with the αβT cell receptor. Berry R, et al. J Biol Chem, 2014 Mar 21. PMID 24488493, Free PMC Article
    3. EST analysis of mRNAs expressed during embryogenesis in Gallus gallus. Jorge EC, et al. Int J Dev Biol, 2004 Jun. PMID 15300514
    4. Splenic gene expression profiling in White Leghorn layer inoculated with the Salmonella enterica serovar Enteritidis. Wu G, et al. Anim Genet, 2015 Dec. PMID 26358731
    5. An expressed sequence tag analysis of the chicken reproductive tract transcriptome. Froman DP, et al. Poult Sci, 2006 Aug. PMID 16903475

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive thymic T cell selection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of alpha-beta T cell receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-cell surface glycoprotein CD3 epsilon chain
    Names
    CD3 epsilon
    CD3E antigen, epsilon polypeptide
    CD3e molecule, epsilon (CD3-TCR complex)
    TiT3 complex

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001397708.1 → NP_001384637.1  T-cell surface glycoprotein CD3 epsilon chain precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has eight exons.
      Source sequence(s)
      AM068697, AM069228, BI391601, BU241154, CD736211, DT655806, JAENSK010000341
      UniProtKB/TrEMBL
      A0A8V0ZXL5
      Conserved Domains (1) summary
      smart00077
      Location:153 → 173
      ITAM; Immunoreceptor tyrosine-based activation motif

    2. NM_001397711.1 → NP_001384640.1  T-cell surface glycoprotein CD3 epsilon chain precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has nine exons.
      Source sequence(s)
      AM068697, AM069228, BI391601, BU241154, CD736211, CD761226, JAENSK010000341
      UniProtKB/TrEMBL
      A0A8V0ZXL5
      Related
      ENSGALP00010035081.1, ENSGALT00010057807.1
      Conserved Domains (1) summary
      smart00077
      Location:153 → 173
      ITAM; Immunoreceptor tyrosine-based activation motif

    3. NM_206904.2 → NP_996787.2  T-cell surface glycoprotein CD3 epsilon chain precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) has six exons.
      Source sequence(s)
      AM068697, AM069228, BI391601, BU241154, CD736211
      UniProtKB/TrEMBL
      A0A8V0ZXL5
      Conserved Domains (1) summary
      smart00077
      Location:153 → 173
      ITAM; Immunoreceptor tyrosine-based activation motif

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052555.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5503915..5511817
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046903737.1 → XP_046759693.1  T-cell surface glycoprotein CD3 epsilon chain isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZXL5

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052596.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5464206..5472104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046932301.1 → XP_046788257.1  T-cell surface glycoprotein CD3 epsilon chain isoform X1

      UniProtKB/TrEMBL
      P70069
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q98910.1 GenPept UniProtKB/Swiss-Prot:Q98910

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials