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    ralaa v-ral simian leukemia viral oncogene homolog Aa (ras related) [ Danio rerio (zebrafish) ]

    Gene ID: 393993, updated on 2-Nov-2024

    Summary

    Official Symbol
    ralaaprovided by ZNC
    Official Full Name
    v-ral simian leukemia viral oncogene homolog Aa (ras related)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1344
    See related
    Ensembl:ENSDARG00000045463 AllianceGenome:ZFIN:ZDB-GENE-040426-1344
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rala; zgc:64038
    Summary
    Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Ras protein signal transduction and regulation of exocytosis. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in lens and solid lens vesicle. Orthologous to human RALA (RAS like proto-oncogene A). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See ralaa in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (1014999..1023146, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (1018955..1027102, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene piezo-type mechanosensitive ion channel component 2 Neighboring gene N-ethylmaleimide-sensitive factor attachment protein, gamma a Neighboring gene si:dkey-192l18.12 Neighboring gene cyclin dependent kinase 13 Neighboring gene si:dkey-192l18.9 Neighboring gene mediator complex subunit 1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC64038

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GDP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ras-related protein Ral-A
    Names
    v-ral simian leukemia viral oncogene homolog A (ras related)
    NP_957312.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201018.1NP_957312.1  ras-related protein Ral-A

      See identical proteins and their annotated locations for NP_957312.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053216
      UniProtKB/TrEMBL
      A0A2R8QA22, F6P431, Q7T383
      Related
      ENSDARP00000066862.3, ENSDART00000066863.5
      Conserved Domains (1) summary
      cd04139
      Location:15177
      RalA_RalB; Ral (Ras-like) family containing highly homologous RalA and RalB

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      1014999..1023146 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)