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    Tmed8 transmembrane p24 trafficking protein 8 [ Mus musculus (house mouse) ]

    Gene ID: 382620, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tmed8provided by MGI
    Official Full Name
    transmembrane p24 trafficking protein 8provided by MGI
    Primary source
    MGI:MGI:1923480
    See related
    Ensembl:ENSMUSG00000034111 AllianceGenome:MGI:1923480
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mem1; Gm1184; 6430595O10Rik
    Summary
    Is expressed in early conceptus. Orthologous to human TMED8 (transmembrane p24 trafficking protein family member 8). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 9.6), frontal lobe adult (RPKM 5.6) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmed8 in Genome Data Viewer
    Location:
    12 D2; 12 41.36 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (87195547..87247264, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (87166242..87200457, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene neuroglobin Neighboring gene protein-O-mannosyltransferase 2 Neighboring gene STARR-positive B cell enhancer ABC_E10770 Neighboring gene STARR-positive B cell enhancer ABC_E10771 Neighboring gene glutathione transferase zeta 1 (maleylacetoacetate isomerase) Neighboring gene predicted gene 6566 Neighboring gene STARR-positive B cell enhancer ABC_E9041 Neighboring gene sterile alpha motif domain containing 15 Neighboring gene NADP+ dependent oxidoreductase domain containing 1 Neighboring gene VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog Neighboring gene AHA1, activator of heat shock protein ATPase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Murine Bv8 gene maps near a synteny breakpoint of mouse chromosome 6 and human 3p21. Jilek A, et al. Gene, 2000 Oct 3. PMID 11054548
    2. Gata2 maps to mouse chromosome 6. Ciciotte SL, et al. Mamm Genome, 1997 Jan. PMID 9021157
    3. New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo. Heyer BS, et al. Mol Reprod Dev, 1997 Jun. PMID 9136115
    4. cDNA cloning and mapping of a novel subtype of glutamine:fructose-6-phosphate amidotransferase (GFAT2) in human and mouse. Oki T, et al. Genomics, 1999 Apr 15. PMID 10198162
    5. Tagging genes with cassette-exchange sites. Cobellis G, et al. Nucleic Acids Res, 2005 Mar 1. PMID 15741177, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein TMED8
    Names
    maternal embryonic message 1
    transmembrane emp24 domain containing 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033475.3 → NP_001028647.1  protein TMED8

      See identical proteins and their annotated locations for NP_001028647.1

      Status: PROVISIONAL

      Source sequence(s)
      AC132609
      Consensus CDS
      CCDS26072.1
      UniProtKB/Swiss-Prot
      Q3UHI4
      UniProtKB/TrEMBL
      B9EKE7
      Related
      ENSMUSP00000043742.6, ENSMUST00000037418.7
      Conserved Domains (1) summary
      pfam13897
      Location:186 → 325
      GOLD_2; Golgi-dynamics membrane-trafficking

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      87195547..87247264 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157514.1 → XP_036013407.1  protein TMED8 isoform X1

      Conserved Domains (1) summary
      pfam13897
      Location:281 → 331
      GOLD_2; Golgi-dynamics membrane-trafficking

    2. XM_030246805.2 → XP_030102665.1  protein TMED8 isoform X3

      Conserved Domains (1) summary
      pfam13897
      Location:76 → 215
      GOLD_2; Golgi-dynamics membrane-trafficking

    3. XM_006516050.5 → XP_006516113.1  protein TMED8 isoform X2

      Conserved Domains (1) summary
      pfam13897
      Location:117 → 256
      GOLD_2; Golgi-dynamics membrane-trafficking
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UHI4.1 GenPept UniProtKB/Swiss-Prot:Q3UHI4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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