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    Tspan13 tetraspanin 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366602, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tspan13provided by RGD
    Official Full Name
    tetraspanin 13provided by RGD
    Primary source
    RGD:1311788
    See related
    EnsemblRapid:ENSRNOG00000005046 AllianceGenome:RGD:1311788
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tm4sf13
    Summary
    Predicted to enable calcium channel regulator activity. Predicted to act upstream of or within regulation of calcium ion transmembrane transport. Predicted to be located in plasma membrane. Orthologous to human TSPAN13 (tetraspanin 13). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 547.7), Lung (RPKM 523.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tspan13 in Genome Data Viewer
    Location:
    6q16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (58466051..58492804, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (52738748..52765503, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (55497659..55524415, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene anterior gradient 3, protein disulphide isomerase family member Neighboring gene anterior gradient 2, protein disulphide isomerase family member Neighboring gene uncharacterized LOC134479367 Neighboring gene basic leucine zipper and W2 domains 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Tetraspanin-13 modulates voltage-gated CaV2.2 Ca2+ channels. Mallmann RT, et al. Sci Rep, 2013. PMID 23648579, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109170

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium channel regulator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of calcium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    tetraspanin-13
    Names
    transmembrane 4 superfamily member 13
    tspan-13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013244.1 → NP_001013262.1  tetraspanin-13

      See identical proteins and their annotated locations for NP_001013262.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089906
      UniProtKB/Swiss-Prot
      Q5FVL6
      UniProtKB/TrEMBL
      A6HBA6
      Related
      ENSRNOP00000006752.3, ENSRNOT00000006752.7
      Conserved Domains (2) summary
      cl02781
      Location:115 → 153
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:55 → 184
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      58466051..58492804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FVL6.1 GenPept UniProtKB/Swiss-Prot:Q5FVL6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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