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    Smg9 SMG9 nonsense mediated mRNA decay factor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 365215, updated on 2-Nov-2024

    Summary

    Official Symbol
    Smg9provided by RGD
    Official Full Name
    SMG9 nonsense mediated mRNA decay factorprovided by RGD
    Primary source
    RGD:1309888
    See related
    EnsemblRapid:ENSRNOG00000019596 AllianceGenome:RGD:1309888
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309888
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including eye development; negative regulation of apoptotic process; and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to act upstream of or within in utero embryonic development. Orthologous to human SMG9 (SMG9 nonsense mediated mRNA decay factor). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 295.3), Thymus (RPKM 60.3) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Smg9 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (89116459..89139182)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79988540..80011262)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (81259450..81282893)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene Ly6/Plaur domain containing 5 Neighboring gene potassium calcium-activated channel subfamily N member 4 Neighboring gene transfer RNA alanine (anticodon AGC) 66 Neighboring gene immunity related GTPase cinema

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in brain development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in brain development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in eye development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in eye development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in eye development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in heart development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in heart development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in in utero embryonic development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    nonsense-mediated mRNA decay factor SMG9
    Names
    protein SMG9
    protein smg-9 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014243.1NP_001014265.1  nonsense-mediated mRNA decay factor SMG9

      See identical proteins and their annotated locations for NP_001014265.1

      Status: VALIDATED

      Source sequence(s)
      BC087051
      UniProtKB/Swiss-Prot
      Q5PQS6
      UniProtKB/TrEMBL
      A0A8L2QFS9, A6J8Y8
      Related
      ENSRNOP00000099692.1, ENSRNOT00000138276.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      89116459..89139182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006228450.5XP_006228512.1  nonsense-mediated mRNA decay factor SMG9 isoform X1

      See identical proteins and their annotated locations for XP_006228512.1

      UniProtKB/Swiss-Prot
      Q5PQS6
      UniProtKB/TrEMBL
      A0A8L2QFS9, A6J8Y8
      Related
      ENSRNOP00000026669.6, ENSRNOT00000026669.8