Retreg2 reticulophagy regulator family member 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Retreg2provided by RGD
Official Full Name: reticulophagy regulator family member 2provided by RGD
Primary source: RGD:1306844
See related: EnsemblRapid:ENSRNOG00000018586 AllianceGenome:RGD:1306844
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam134a; RGD1306844
Summary: Predicted to enable endoplasmic reticulum-autophagosome adaptor activity. Predicted to act upstream of or within collagen catabolic process; endoplasmic reticulum organization; and reticulophagy. Predicted to be located in endoplasmic reticulum. Predicted to be active in membrane. Orthologous to human RETREG2 (reticulophagy regulator family member 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 279.4), Kidney (RPKM 142.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 9q33

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (84088935..84095072)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (76640282..76646400)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (82345686..82351800)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI236911 (e-PCR)
- UniSTS:250667

D9Mco45 (e-PCR)
- UniSTS:518480

RH66353 (e-PCR)
- UniSTS:12120

RH130716 (e-PCR)
- UniSTS:214000

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables endoplasmic reticulum-autophagosome adaptor activity	IEA Inferred from Electronic Annotation more info
enables endoplasmic reticulum-autophagosome adaptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in collagen catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within collagen catabolic process	ISO Inferred from Sequence Orthology more info
involved_in endoplasmic reticulum organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within endoplasmic reticulum organization	ISO Inferred from Sequence Orthology more info
involved_in reticulophagy	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within reticulophagy	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: reticulophagy regulator 2

Names: family with sequence similarity 134, member A; protein FAM134A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.