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    Tmed9 transmembrane p24 trafficking protein 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361207, updated on 2-Nov-2024

    Summary

    Official Symbol
    Tmed9provided by RGD
    Official Full Name
    transmembrane p24 trafficking protein 9provided by RGD
    Primary source
    RGD:1307627
    See related
    EnsemblRapid:ENSRNOG00000021882 AllianceGenome:RGD:1307627
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307627
    Summary
    Predicted to enable syntaxin binding activity. Predicted to be involved in several processes, including Golgi organization; Golgi vesicle transport; and intracellular protein transport. Predicted to be located in synaptic vesicle. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human TMED9 (transmembrane p24 trafficking protein 9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 489.0), Lung (RPKM 351.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmed9 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (9034797..9039311, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (9029646..9034160, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (9560735..9565249, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene calcium modulating ligand Neighboring gene beta-1,4-galactosyltransferase 7 Neighboring gene family with sequence similarity 193, member B Neighboring gene uncharacterized LOC108348505 Neighboring gene microRNA 3542 Neighboring gene DEAD-box helicase 41

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC95048

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables syntaxin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables syntaxin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in COPI coating of Golgi vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in COPI coating of Golgi vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in COPI coating of Golgi vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in Golgi organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    NOT involved_in early endosome to Golgi transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of organelle organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of organelle organization ISO
    Inferred from Sequence Orthology
    more info
     
    NOT involved_in protein exit from endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transmembrane emp24 domain-containing protein 9
    Names
    p24 family protein alpha-2
    p24alpha2
    transmembrane emp24 protein transport domain containing 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009703.1NP_001009703.1  transmembrane emp24 domain-containing protein 9 precursor

      See identical proteins and their annotated locations for NP_001009703.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088422
      UniProtKB/Swiss-Prot
      Q5I0E7
      UniProtKB/TrEMBL
      A0A8L2UKN3
      Related
      ENSRNOP00000030668.6, ENSRNOT00000036140.8
      Conserved Domains (1) summary
      pfam01105
      Location:37230
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      9034797..9039311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)