Suco SUN domain containing ossification factor [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Sucoprovided by RGD
Official Full Name: SUN domain containing ossification factorprovided by RGD
Primary source: RGD:735185
See related: EnsemblRapid:ENSRNOG00000026542 AllianceGenome:RGD:735185
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Dd25
Summary: Predicted to be involved in positive regulation of collagen biosynthetic process; positive regulation of osteoblast differentiation; and regulation of bone remodeling. Predicted to be located in rough endoplasmic reticulum. Predicted to be active in cytoplasm and membrane. Orthologous to human SUCO (SUN domain containing ossification factor). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Adrenal (RPKM 174.6), Spleen (RPKM 156.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q22

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (76726095..76791174, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (74192808..74257896, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (79736485..79801133, complement)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BF398732 (e-PCR)
- UniSTS:246901

BE119592 (e-PCR)
- UniSTS:249219

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in ossification	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of collagen biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of collagen biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of collagen biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of osteoblast differentiation	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of osteoblast differentiation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of osteoblast differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of bone remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of bone remodeling	IEA Inferred from Electronic Annotation more info
involved_in regulation of bone remodeling	ISO Inferred from Sequence Orthology more info
involved_in regulation of bone remodeling	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in rough endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in rough endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in rough endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
located_in rough endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: SUN domain-containing ossification factor

Names: SUN-like protein 1; hypothetical protein Dd25; membrane protein CH1; protein C1orf9 homolog; protein osteopotentia homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199403.4 → NP_955435.4 SUN domain-containing ossification factor precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000013

Related

ENSRNOP00000071346.3, ENSRNOT00000084058.3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086031.1 Reference GRCr8

Range

76726095..76791174 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063272485.1 → XP_063128555.1 SUN domain-containing ossification factor isoform X6
XM_006250166.5 → XP_006250228.3 SUN domain-containing ossification factor isoform X5
XM_006250164.5 → XP_006250226.3 SUN domain-containing ossification factor isoform X3
XM_008769658.4 → XP_008767880.3 SUN domain-containing ossification factor isoform X4
XM_017598851.3 → XP_017454340.3 SUN domain-containing ossification factor isoform X2
XM_008769657.4 → XP_008767879.3 SUN domain-containing ossification factor isoform X1

Related

ENSRNOP00000068027.3, ENSRNOT00000075936.4
XM_039090908.2 → XP_038946836.2 SUN domain-containing ossification factor isoform X7