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    Nse4 Non-SMC element 4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34434, updated on 2-Nov-2024

    Summary

    Official Symbol
    Nse4provided by FlyBase
    Official Full Name
    Non-SMC element 4provided by FlyBase
    Primary source
    FLYBASE:FBgn0032251
    Locus tag
    Dmel_CG13142
    See related
    AllianceGenome:FB:FBgn0032251
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13142; Dmel\CG13142
    Summary
    Predicted to be involved in DNA repair. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Orthologous to human EID3 (EP300 interacting inhibitor of differentiation 3) and NSMCE4A (NSE4 homolog A, SMC5-SMC6 complex component). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See Nse4 in Genome Data Viewer
    Location:
    31E2-31E2; 2-42 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10439440..10441047)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10439440..10441047)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene hole-in-one Neighboring gene STIP1 homology and U-box containing protein 1 Neighboring gene long non-coding RNA:CR45375 Neighboring gene lonely heart

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA repair ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of Smc5-Smc6 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Smc5-Smc6 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Smc5-Smc6 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    Non-SMC element 4
    Names
    CG13142-PB
    CG13142-PC
    Nse4-PB
    Nse4-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10439440..10441047
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135561.3NP_609405.2  Non-SMC element 4, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609405.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QQ24, Q4QQ37, Q9VKV4
      Conserved Domains (1) summary
      pfam08743
      Location:200282
      Nse4_C; Nse4 C-terminal
    2. NM_001169467.1NP_001162938.1  Non-SMC element 4, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162938.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QQ24, Q4QQ37, Q9VKV4
      Conserved Domains (1) summary
      pfam08743
      Location:200282
      Nse4_C; Nse4 C-terminal