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    Tceal5 transcription elongation factor A (SII)-like 5 [ Mus musculus (house mouse) ]

    Gene ID: 331532, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tceal5provided by MGI
    Official Full Name
    transcription elongation factor A (SII)-like 5provided by MGI
    Primary source
    MGI:MGI:3036236
    See related
    Ensembl:ENSMUSG00000054034 AllianceGenome:MGI:3036236
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6430401A05Rik
    Summary
    Predicted to be located in nucleus. Is expressed in several structures, including ganglia; gut; lung; remnant of Rathke's pouch; and sensory organ. Orthologous to human TCEAL5 (transcription elongation factor A like 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in frontal lobe adult (RPKM 53.5), cortex adult (RPKM 43.7) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tceal5 in Genome Data Viewer
    Location:
    X F1; X 57.4 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135101697..135104633, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136200948..136203884, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene microRNA 6383 Neighboring gene predicted gene, 41901 Neighboring gene nuclear encoded tRNA lysine 19 (anticodon CTT) Neighboring gene STARR-seq mESC enhancer starr_47976 Neighboring gene predicted gene, 51612 Neighboring gene brain expressed X-linked 1 Neighboring gene transcription elongation factor A (SII)-like 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Tceal5 and Tceal7 Function in C2C12 Myogenic Differentiation via Exosomes in Fetal Bovine Serum. Sawada A, et al. Int J Mol Sci, 2022 Feb 12. PMID 35216152, Free PMC Article
    2. Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation. Gergics P, et al. Endocrinology, 2016 Sep. PMID 27580811, Free PMC Article
    3. SDS3 interacts with ARNT in an AhR ligand-specific manner regulating expression of cKrox and S100A4 in CD4+CD8+ DPK thymocytes differentiation. Lee DM, et al. Environ Toxicol Pharmacol, 2012 Nov. PMID 22981438
    4. Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Navas-Pérez E, et al. Genome Biol, 2020 Oct 26. PMID 33100228, Free PMC Article
    5. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Tceal5 and Tceal7 Function in C2C12 Myogenic Differentiation via Exosomes in Fetal Bovine Serum.
      Title: Tceal5 and Tceal7 Function in C2C12 Myogenic Differentiation via Exosomes in Fetal Bovine Serum.
    2. sufficient to increase the growth rate of pituitary progenitors, suggesting a role as a proto-oncogene
      Title: Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transcription elongation factor A protein-like 5
    Names
    TCEA-like protein 5
    transcription elongation factor S-II protein-like 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001365117.1 → NP_001352046.1  transcription elongation factor A protein-like 5

      Status: VALIDATED

      Source sequence(s)
      AK032140, BE991033, BY136503
      Consensus CDS
      CCDS30416.1
      UniProtKB/Swiss-Prot
      Q497R6, Q8CCT4
      UniProtKB/TrEMBL
      Q14C38
      Conserved Domains (1) summary
      pfam04538
      Location:55 → 170
      BEX; Brain expressed X-linked like family

    2. NM_001365118.1 → NP_001352047.1  transcription elongation factor A protein-like 5

      Status: VALIDATED

      Source sequence(s)
      AL772180
      Consensus CDS
      CCDS30416.1
      UniProtKB/Swiss-Prot
      Q497R6, Q8CCT4
      UniProtKB/TrEMBL
      Q14C38
      Conserved Domains (1) summary
      pfam04538
      Location:55 → 170
      BEX; Brain expressed X-linked like family

    3. NM_177919.3 → NP_808587.1  transcription elongation factor A protein-like 5

      See identical proteins and their annotated locations for NP_808587.1

      Status: VALIDATED

      Source sequence(s)
      AK032140, BE991033, BY245586
      Consensus CDS
      CCDS30416.1
      UniProtKB/Swiss-Prot
      Q497R6, Q8CCT4
      UniProtKB/TrEMBL
      Q14C38
      Related
      ENSMUSP00000065397.5, ENSMUST00000066819.11
      Conserved Domains (1) summary
      pfam04538
      Location:55 → 170
      BEX; Brain expressed X-linked like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      135101697..135104633 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CCT4.1 GenPept UniProtKB/Swiss-Prot:Q8CCT4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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